Increasing susceptibility to HAV among members of the young generation in Thailand.

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dc.contributor.authorPoovorawan, Yen_US
dc.contributor.authorTheamboonlers, Aen_US
dc.contributor.authorSinlaparatsamee, Sen_US
dc.contributor.authorChaiear, Ken_US
dc.contributor.authorSiraprapasiri, Ten_US
dc.contributor.authorKhwanjaipanich, Sen_US
dc.contributor.authorOwatanapanich, Sen_US
dc.contributor.authorHirsch, Pen_US
dc.date.accessioned2009-05-27T17:08:37Z
dc.date.available2009-05-27T17:08:37Z
dc.date.issued2000-12-24en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractThe prevalence of antibodies to hepatitis A virus was studied in 961 children and adolescents, randomly selected from five different provinces in Thailand (Chonburi, Lopburi, Udonthani, Nakhon Si Thammarat and Lopburi). The highest prevalence was found in Nakhon Si Thammarat, with 32.1 percent of those aged 10-14 years and 57.1 percent of those aged 15-18 years showing evidence of protective immunity. However, this high rate could be explained by an outbreak of hepatitis A in 1992. In the remaining four provinces, the pattern was typically age-related in that all individuals showed between zero and 13 percent antibody prevalence until reaching the 15-to-18-year age group where it increased to between 5.6 and 22.7 percent. The overall sero-prevalence among all age groups was 7.9 percent. Thus, the majority of the younger generation is susceptible to hepatitis A virus infection thereby enhancing the impact, should an outbreak occur. Preventive measures that might be taken are education aimed at better hygiene and sanitation, as well as vaccination of susceptible individuals within high-risk populations.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University & Hospital, Bangkok, Thailand.en_US
dc.identifier.citationPoovorawan Y, Theamboonlers A, Sinlaparatsamee S, Chaiear K, Siraprapasiri T, Khwanjaipanich S, Owatanapanich S, Hirsch P. Increasing susceptibility to HAV among members of the young generation in Thailand. Asian Pacific Journal of Allergy and Immunology. 2000 Dec; 18(4): 249-53en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36545
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDisease Susceptibility --immunologyen_US
dc.subject.meshHepatitis A --epidemiologyen_US
dc.subject.meshHepatitis A Antibodiesen_US
dc.subject.meshHepatitis Antibodies --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleIncreasing susceptibility to HAV among members of the young generation in Thailand.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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