Pre-administration of beta-carotene protects tissue glutathione and lipid peroxidation status following exposure to gamma radiation.

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dc.contributor.authorManda, Ken_US
dc.contributor.authorBhatia, A Len_US
dc.date.accessioned2003-10-14en_US
dc.date.accessioned2009-06-02T04:30:37Z
dc.date.available2003-10-14en_US
dc.date.available2009-06-02T04:30:37Z
dc.date.issued2003-10-14en_US
dc.description.abstractThe present study has been aimed to investigate the protective effect of beta-carotene against radiation-induced oxidative stress in mice tissues using lipid peroxidation and glutathione (GSH) as end points. Fourteen days oral priming administration of beta-carotene (35 mg/kg body weight) followed by an acute dose of gamma radiation (5 Gy) inhibited the augmented level of thiobarbituric acid reactive substance (TBARS) and a statistically significant protection against GSH depletion. Results evaluated from this study clearly indicate the antioxidative property of beta-carotene against gamma radiation, which is suggestive of free radical scavenging and singlet oxygen quenching.en_US
dc.description.affiliationRadiation Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur-302 004, India.en_US
dc.identifier.citationManda K, Bhatia AL. Pre-administration of beta-carotene protects tissue glutathione and lipid peroxidation status following exposure to gamma radiation. Journal of Environmental Biology. 2003 Oct; 24(4): 369-72en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/113821
dc.language.isoengen_US
dc.source.urihttps://www.geocities.com/j_environ_biol/en_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntioxidants --pharmacologyen_US
dc.subject.meshBrain --metabolismen_US
dc.subject.meshGamma Raysen_US
dc.subject.meshGlutathione --drug effectsen_US
dc.subject.meshKidney --metabolismen_US
dc.subject.meshLipid Peroxidation --drug effectsen_US
dc.subject.meshLiver --metabolismen_US
dc.subject.meshLung --metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshSpleen --metabolismen_US
dc.subject.meshTestis --metabolismen_US
dc.subject.meshThiobarbituric Acid Reactive Substances --metabolismen_US
dc.subject.meshbeta Carotene --pharmacologyen_US
dc.titlePre-administration of beta-carotene protects tissue glutathione and lipid peroxidation status following exposure to gamma radiation.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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