Lipid peroxidation in hepatic microsomal membranes isolated from mice in health and in experimental leishmaniasis.

Simple item page
dc.contributor.authorBagchi, Men_US
dc.contributor.authorMukherjee, Sen_US
dc.contributor.authorBasu, M Ken_US
dc.date.accessioned1993-10-01en_US
dc.date.accessioned2009-05-27T09:39:54Z
dc.date.available1993-10-01en_US
dc.date.available2009-05-27T09:39:54Z
dc.date.issued1993-10-01en_US
dc.description.abstractNormal hepatic microsomal membranes when exposed in vitro to different free radicals, cause membrane damage by lipid peroxidation which could be monitored by the analysis of malonaldehyde formation and measurement of membrane microviscosity. Lipid peroxidation in vivo, when examined in hepatic microsomal membranes in experimental Leishmaniasis, reveals a direct relationship between membrane microviscosity and the extent of lipid peroxidation. Scavengers of free radicals and peroxides such as superoxide dismutase (SOD) for O2.-, mannitol for (OH.) and catalase for H2O2 in modest amounts were used for preventing the membrane damage caused by lipid peroxidation.en_US
dc.description.affiliationBiomembrane Division, Indian Institute of Chemical Biology, Calcutta.en_US
dc.identifier.citationBagchi M, Mukherjee S, Basu MK. Lipid peroxidation in hepatic microsomal membranes isolated from mice in health and in experimental leishmaniasis. Indian Journal of Biochemistry & Biophysics. 1993 Oct; 30(5): 277-81en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/28191
dc.language.isoengen_US
dc.source.urihttps://https://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijbb/ijbb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshFree Radical Scavengersen_US
dc.subject.meshIntracellular Membranes --drug effectsen_US
dc.subject.meshLeishmania donovanien_US
dc.subject.meshLeishmaniasis, Visceral --metabolismen_US
dc.subject.meshLipid Peroxidation --drug effectsen_US
dc.subject.meshMalondialdehyde --metabolismen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred BALB Cen_US
dc.subject.meshMicrosomes, Liver --drug effectsen_US
dc.subject.meshOxidants --pharmacologyen_US
dc.subject.meshReference Valuesen_US
dc.titleLipid peroxidation in hepatic microsomal membranes isolated from mice in health and in experimental leishmaniasis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Biochemistry & Biophysics