Avoidance learning under hypo and hyperglycemia in rats.

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dc.contributor.authorAgrawal, J Ken_US
dc.contributor.authorThombre, D Pen_US
dc.date.accessioned1990-04-01en_US
dc.date.accessioned2009-06-01T08:18:18Z
dc.date.available1990-04-01en_US
dc.date.available2009-06-01T08:18:18Z
dc.date.issued1990-04-01en_US
dc.description.abstractLearning behaviour under different glycaemic conditions were studied in albino rats using an avoidance box. When insulin and glucose levels were low after fasting, animals showed delay in avoidance learning. But there was no change in acquisition of learning after hypoglacaemia induced by insulin. This difference in behaviour under hypoglycaemia of almost similar severity is possibly due to difference in its rate of induction and activation of counter regulatory neuro-endocrine mechanisms. Diabetic (alloxan) rats failed to improve learning. Besides, hyperglycemia, other factors like metabolic disturbances, cytotoxic effects of alloxan may have inhibited learning in this group. Hypo or hyperglycemia disturb the function of neuronal substrates responsible for learning and memory.en_US
dc.description.affiliationDepartment of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.en_US
dc.identifier.citationAgrawal JK, Thombre DP. Avoidance learning under hypo and hyperglycemia in rats. Indian Journal of Physiology and Pharmacology. 1990 Apr; 34(2): 105-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108811
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAvoidance Learning --drug effectsen_US
dc.subject.meshBlood Glucose --metabolismen_US
dc.subject.meshDiabetes Mellitus, Experimental --psychologyen_US
dc.subject.meshHyperglycemia --psychologyen_US
dc.subject.meshHypoglycemia --psychologyen_US
dc.subject.meshInsulin --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshRatsen_US
dc.titleAvoidance learning under hypo and hyperglycemia in rats.en_US
dc.typeJournal Articleen_US
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