Treatment Of Severe Hyperbilirubinemia Through Coupled Plasma Filtration Adsorption

Simple item page
dc.contributor.authorDambruoso, Pierpaoloen_US
dc.contributor.authorNicola, Cappellanoen_US
dc.contributor.authorPasquale, Raimondoen_US
dc.date.accessioned2020-01-02T06:28:55Z
dc.date.available2020-01-02T06:28:55Z
dc.date.issued2018-09
dc.description.abstractThe development of severe hyperbilirubinemia after cardiac surgery performed with cardiopulmonary bypass is a possible life-threatening challenging complication because its mechanism is still not completely clarified, and there are only a few specific therapies available for acute hepatobiliary injury. Here, we report the case of an 80-year-old male scheduled for elective aortic valve replacement, during the 1st post-operative day (POD 1), developed acute systo-diastolic cardiac failure, with a severe aortic paravalvular leak. The surgeon decided reoperation to correct prosthesis dehiscence. There was a continuous total serum bilirubin increase, with a peak value of 24.50 mg/dl on POD 16. It was diagnosed as a “cholestatic post-cardiac surgery syndrome,” and we performed seven cycles of coupled plasma filtration adsorption (CPFA), with definitive stable bilirubinemia reduction to 3.0 mg/dl at the discharge. CPFA was found to be a good hemodepurative technique to manage successfully severe hyperbilirubinemia of “cholestatic post-cardiac surgery syndrome.”en_US
dc.identifier.affiliationsDepartment of Cardiac Anaesthesia and Intensive Care Unit, Santa Maria Hospital-GVM Care and Research, Via De Ferrariis 22, 70124 Bari, Italyen_US
dc.identifier.citationDambruoso Pierpaolo, Nicola Cappellano, Pasquale Raimondo. Treatment Of Severe Hyperbilirubinemia Through Coupled Plasma Filtration Adsorption. Indian Journal of Case Reports. 2018 Sep; 4(5): 353-355en_US
dc.identifier.issn2454-129X
dc.identifier.issn2454-1303
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190431
dc.languageenen_US
dc.publisherAtharva Scientific Publicationsen_US
dc.relation.issuenumber5en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.32677/IJCR.2018.v04.i05.005en_US
dc.titleTreatment Of Severe Hyperbilirubinemia Through Coupled Plasma Filtration Adsorptionen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijcr2018v4n5p353.pdf
Size:
270.83 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Case Reports