Granulomatosis with Polyangiitis Presenting as a Renal Mass: A Scarce Case Report with a Review of the Literature

Simple item page
dc.contributor.authorKumar, Manjeeten_US
dc.contributor.authorBarwal, Kailash Chanderen_US
dc.contributor.authorSharma, Sunishen_US
dc.contributor.authorChauhan, Sanjeeven_US
dc.contributor.authorRaina, Pamposhen_US
dc.date.accessioned2023-07-21T11:28:16Z
dc.date.available2023-07-21T11:28:16Z
dc.date.issued2023-01
dc.description.abstractWegener granulomatosis (WG) now known as granulomatosis with polyangiitis (GPA) is an uncommon autoimmune disorder of undivulged etiology affecting the respiratory tract including paranasal sinuses, nasal cavity, lungs, and kidneys predominantly. GPA presenting as a solitary renal mass is rarely seen. We present a case report of a 27-year-old female presenting with a right renal mass along with pain, low-grade fever, and arthralgia. Computed tomography scan of the abdomen revealed a hypodense low attenuated renal mass with indistinct margins. Ultrasound-guided biopsy revealed features typical of GPA. She was started on oral steroids (prednisolone 40?mg) and azathioprine. She developed pain, vomiting, and diarrhea after starting treatment with azathioprine. Azathioprine was stopped and rituximab 1?g weekly was started for 4 weeks followed by 500?mg 6 monthly injections. She got symptomatic relief at 4 weeks with a diminution of renal mass at 6 months follow-up. We report this rare entity of WG presenting as renal mass. Suspecting and diagnosing renal mass as a part of GPA prevented us from undertaking unnecessary surgical treatment in this patient. Medical treatment with steroids and rituximab is effective in inducing remission and maintenance.en_US
dc.identifier.affiliationsDepartment of Urology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Urology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Urology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Urology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.citationKumar, Manjeeten_US
dc.identifier.citationBarwal, Kailash Chanderen_US
dc.identifier.citationSharma, Sunishen_US
dc.identifier.citationChauhan, Sanjeeven_US
dc.identifier.citationRaina, Pamposh. Granulomatosis with Polyangiitis Presenting as a Renal Mass: A Scarce Case Report with a Review of the Literature. Annals of the National Academy of Medical Sciences. 2023 Jan; 59(1): 55-59en_US
dc.identifier.issn0379-038X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220220
dc.languageenen_US
dc.publisherThieme Medical and Scientific Publishers Pvt. Ltden_US
dc.relation.issuenumber1en_US
dc.relation.volume59en_US
dc.source.urihttps://doi.org/10.1055/s-0042-1760352en_US
dc.subjectWegener granulomatosisen_US
dc.subjectgranulomatosis with polyangiitisen_US
dc.subjectimmunosuppressive therapyen_US
dc.titleGranulomatosis with Polyangiitis Presenting as a Renal Mass: A Scarce Case Report with a Review of the Literatureen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ANAMS2023v59n1p55.pdf
Size:
4.74 MB
Format:
Adobe Portable Document Format
Download
Collections
Annals of the National Academy of Medical Sciences (India)