Angiographic profile and outcomes in persistent non-valvular atrial fibrillation: A study from tertiary care center in North India

Simple item page
dc.contributor.authorSharma, Yash Paulen_US
dc.contributor.authorBatta, Akashen_US
dc.contributor.authorMakkar, Kunaalen_US
dc.contributor.authorHatwal, Junialien_US
dc.contributor.authorGawalkar, Atit Aen_US
dc.contributor.authorKaur, Navjyoten_US
dc.contributor.authorMalhi, Tejinder Singhen_US
dc.contributor.authorKasinadhuni, Ganeshen_US
dc.contributor.authorGupta, Himanshuen_US
dc.contributor.authorPanda, Prashanten_US
dc.contributor.authorBarwad, Paragen_US
dc.date.accessioned2023-07-21T11:36:52Z
dc.date.available2023-07-21T11:36:52Z
dc.date.issued2022-02
dc.description.abstractBackground: The relationship of atrial fibrillation (AF) with coronary artery disease (CAD) is well established, yet it is often missed. There is evidence of myocardial ischemia on stress imaging in AF patients in the absence of obstructive CAD. In this prospective cohort, we studied the angiographic profiles of non-valvular AF patients. Methods: The study was a nonrandomized, prospective, single-center observational study of consecutive patients of persistent non-valvular AF. Patients symptomatic for AF despite optimal medical therapy for 3 months were recruited and all underwent coronary angiograms (CAG). Patients with prior history of CAD were excluded. Results: A total of 70 patients were followed for a mean duration of 12 ± 1.4 months. The mean age of the study group was 66.07 (±11.49) years. Hypertension was the commonest comorbidity seen in 74% patients. Obstructive CAD was present in 32 (46%) patients, non-obstructive (<50% stenosis) CAD in 17 (24%) patients and normal coronaries in 21 (30%) patients. Overall 49 (70%) patients had evidence of CAD. Amongst patients without obstructive CAD, slow flow was seen in 16 (42%) patients. Lower baseline ejection fraction, lower haemoglobin & albumin levels and higher creatinine levels was associated with increased mortality. In patients without obstructive CAD, hospitalizations for fast ventricular rate were significantly increased in those having slow flow on CAG (p ¼ 0.005). Conclusions: Majority (70%) of our patients had evidence of atherosclerotic CAD on CAG. A large proportion of patients without obstructive CAD had slow flow on CAG.en_US
dc.identifier.affiliationsDepartment of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education & Research, Chandigarh, 160012, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, Advanced Cardiac Centre, Post Graduate Institute of Medical Education & Research, Chandigarh, 160012, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Dayanand Medical college and hospital, Ludhiana, Punjab, 141001, Indiaen_US
dc.identifier.citationSharma Yash Paul, Batta Akash, Makkar Kunaal, Hatwal Juniali, Gawalkar Atit A, Kaur Navjyot, Malhi Tejinder Singh, Kasinadhuni Ganesh, Gupta Himanshu, Panda Prashant, Barwad Parag . Angiographic profile and outcomes in persistent non-valvular atrial fibrillation: A study from tertiary care center in North India. Indian Heart Journal. 2022 Feb; 74(1): 7-12en_US
dc.identifier.issn0019-4832
dc.identifier.issn2213-3763
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220877
dc.languageenen_US
dc.publisherCardiological Society of Indiaen_US
dc.relation.issuenumber1en_US
dc.relation.volume74en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2021.12.010en_US
dc.subjectAtrial fibrillationen_US
dc.subjectCoronary angiographyen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectCoronary slow flowen_US
dc.subjectFast ventricular rateen_US
dc.titleAngiographic profile and outcomes in persistent non-valvular atrial fibrillation: A study from tertiary care center in North Indiaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IHJ2022v74n1p7.pdf
Size:
418.66 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Heart Journal