Etiologies of central diabetes insipidus in children : 15 years experience in Songklanagarind hospital, Thailand.

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dc.contributor.authorJaruratanasirikul, Somchiten_US
dc.contributor.authorJanjindamai, Supachaien_US
dc.contributor.authorSriplung, Hutchaen_US
dc.contributor.authorPatarakijvanich, Narumonen_US
dc.contributor.authorVasiknanonte, Punneeen_US
dc.date.accessioned2009-05-27T18:59:30Z
dc.date.available2009-05-27T18:59:30Z
dc.date.issued2002-07-26en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractCentral diabetes insipidus (DI) is a rare disease in children. The authors retrospectively reviewed the records of children with central DI identified at Songklanagarind Hospital from 1985 to 2000. Of the total 29 patients identified, 16 patients were males and 13 were females. All patients received computed tomography or magnetic resonance imaging of the brain to differentiate the etiologies of central DI. The median age at diagnosis was 6.6 years (range 1.5-14.9). The etiologies of central DI were intracranial tumors in 7 patients (24.1%), histiocytosis in 3 patients (10.3%), septooptic dysplasia in 1 patient (3.5%), empty-sella syndrome in 1 patient (3.5%), pituitary abscess in 1 patient (3.5%), and idiopathic in 16 patients (55.1%). All patients with idiopathic central DI were followed-up for a median duration of 4.5 years (range 1.3-15.5). Three of 16 patients (18.8%) were found to have intracranial tumors at 1.3, 2.3, and 3.5 years of follow-up. It was also observed that the patients whose age at presentation was less than 5 years (histiocytosis was excluded) were less likely to have intracranial tumors than those older than 5 years, (0% vs 55%), with significant statistical difference (p<0.01). It is concluded that: 1) the common etiologies of central DI are intracranial tumor and idiopathic, 2) patients initially diagnosed with idiopathic central DI need to have long-term follow-up by magnetic resonance imaging to identify any occult intracerebral tumor.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Thailand.en_US
dc.identifier.citationJaruratanasirikul S, Janjindamai S, Sriplung H, Patarakijvanich N, Vasiknanonte P. Etiologies of central diabetes insipidus in children : 15 years experience in Songklanagarind hospital, Thailand. Journal of the Medical Association of Thailand. 2002 Jul; 85(7): 765-71en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/40255
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDiabetes Insipidus, Neurogenic --etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitals --statistics & numerical dataen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshThailanden_US
dc.subject.meshTime Factorsen_US
dc.titleEtiologies of central diabetes insipidus in children : 15 years experience in Songklanagarind hospital, Thailand.en_US
dc.typeJournal Articleen_US
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