Effect of various pharmacological agonists on the rat caecum-appendix preparation: a preliminary study.

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1982-10-01
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A preliminary study with various pharmacological agents revealed the presence of contractile muscarinic and H1-histamine receptors as well as inhibitory alpha- and beta-adrenoceptors and purinoceptors in rat caecum-appendix. Histamine also produced indirect actions mediated through the release of catecholamines. 5-Hydroxytryptamine produced variable response, the contractile response was mediated through 5-HT receptors and the relaxant response through the release of catecholamines.
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Mehta AK, Kulkarni SK, Singh M. Effect of various pharmacological agonists on the rat caecum-appendix preparation: a preliminary study. Indian Journal of Physiology and Pharmacology. 1982 Oct-Dec; 26(4): 284-8