Rapid staining using toluidine blue: a reliable method for quick diagnosis in ultrasound-guided aspiration cytology.

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dc.contributor.authorJoy, M Pen_US
dc.contributor.authorIyer, Venkateswaran Ken_US
dc.contributor.authorAron, Manjuen_US
dc.contributor.authorKapila, Kusumen_US
dc.contributor.authorVerma, Kusumen_US
dc.date.accessioned2003-10-18en_US
dc.date.accessioned2009-05-29T11:54:04Z
dc.date.available2003-10-18en_US
dc.date.available2009-05-29T11:54:04Z
dc.date.issued2003-10-18en_US
dc.description.abstractRapid staining of ultrasound guided aspirates is an accepted procedure for evaluation of adequacy and rapid diagnosis (RD). We have assessed the reliability of Toluidine blue stain in this regard, which has not been previously reported. 295 ultrasound guided aspirates performed over a 13 month period were studied. 59 aspirates were inadequate for RD. 103 cases were called malignant on RD of which 101 were confirmed, and 2 cases were considered highly suspicious on final diagnosis. Of 34 cases considered suspicious on RD, 32 were either signed out as malignant or considered highly suspicious while 2 cases were benign. Of 56 cases considered benign on RD, 49 were confirmed, 2 were suspicious for malignancy and 5 cases had inadequate material on final diagnosis. All 43 inflammatory lesions on RD were confirmed. The overall sensitivity for a malignant/suspicious for malignancy diagnosis was 98.54% on RD while specificity was 97.99%. Sensitivity and specificity for an inflammatory condition was 100%. Toluidine blue staining is not only a reliable method for rapid staining and diagnosis, it also permits preservation of cytological material by destaining and restaining with permanent stains.en_US
dc.description.affiliationDepartment of Pathology, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationJoy MP, Iyer VK, Aron M, Kapila K, Verma K. Rapid staining using toluidine blue: a reliable method for quick diagnosis in ultrasound-guided aspiration cytology. Indian Journal of Pathology & Microbiology. 2003 Oct; 46(4): 589-92en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74015
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshBiopsy, Fine-Needleen_US
dc.subject.meshColoring Agentsen_US
dc.subject.meshCytodiagnosis --methodsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshStaining and Labeling --methodsen_US
dc.subject.meshTolonium Chlorideen_US
dc.subject.meshUltrasonicsen_US
dc.titleRapid staining using toluidine blue: a reliable method for quick diagnosis in ultrasound-guided aspiration cytology.en_US
dc.typeJournal Articleen_US
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