Effectiveness of alpha-beta arteether in clearing Plasmodium falciparum parasitemia in central India (Madhya Pradesh).

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dc.contributor.authorSingh, Nen_US
dc.contributor.authorShukla, M Men_US
dc.contributor.authorAsthana, O Pen_US
dc.contributor.authorSharma, V Pen_US
dc.date.accessioned2009-05-27T15:26:16Z
dc.date.available2009-05-27T15:26:16Z
dc.date.issued1998-06-14en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractForty-six patients (25 Females + 21 Males) of uncomplicated Plasmodium falciparum in districts Jabalpur and Mandla of central India (Madhya Pradesh) were administered alpha-beta arteether (an ethyl derivative of qinghaosu), intramuscularly for 3 consecutive days (150 mg once a day). The results revealed that there was rapid control of fever in all the patients without administration of any antipyretic drug. The mean parasite clearance time was 30.78 +/- 10.92 hours and recrudescence/reinfection rate was 6.7% within 28 days. Study indicates that arteether, besides being a potent and fast acting schizontocidal drug, also exhibited gametocytocidal action on P. falciparum.en_US
dc.description.affiliationMalaria Research Center (Field Station), Medical College Building, Jabalpur, India.en_US
dc.identifier.citationSingh N, Shukla MM, Asthana OP, Sharma VP. Effectiveness of alpha-beta arteether in clearing Plasmodium falciparum parasitemia in central India (Madhya Pradesh). The Southeast Asian Journal of Tropical Medicine and Public Health. 1998 Jun; 29(2): 225-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/32786
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntimalarials --pharmacologyen_US
dc.subject.meshArtemisininsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMalaria, Falciparum --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshParasitemia --drug therapyen_US
dc.subject.meshPlasmodium falciparum --drug effectsen_US
dc.subject.meshSesquiterpenes --pharmacologyen_US
dc.titleEffectiveness of alpha-beta arteether in clearing Plasmodium falciparum parasitemia in central India (Madhya Pradesh).en_US
dc.typeClinical Trialen_US
dc.typeClinical Trial, Phase IIIen_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
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