Transfusion of Blood and Components in Critically Ill Children.
Loading...
Date
2010-12
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The physicians prescribing transfusions must
have a thorough understanding of the various blood
products, their indications and contraindications, and
requirements for modification of the blood products to
prevent probable adverse effects. Decision to give an RBC
transfusion should not be based solely on Hb concentration,
it should take in account high severity of illness; active
bleeding; emergency surgery; etc. Using restrictive transfusion
strategy of transfusion RBCs can decrease transfusion
requirements without increasing adverse outcomes. In most
circumstances, platelets should be maintained greater than
10×109/L. Platelet counts greater than 20×109/L are
indicated for invasive procedures and greater than 50×
109/L for major surgeries or invasive procedures with risk
of bleeding. Whenever possible, ABO-compatible platelets
should be administered. Fresh frozen plasma should be
transfused in multiple coagulation factor deficiencies, DIC
with bleeding, replacement of rare single congenital factor
deficiencies when specific concentrates are not available
(e.g., protein C or factor II, V, X, XI, or XIII deficiency).
During transfusion child should be monitored carefully.
Description
Keywords
Blood component therapy, Fresh frozen plasma, Platelets, Red blood cells, Critically ill children
Citation
Uppal Preena, Lodha Rakesh, Kabra Sushil K. Transfusion of Blood and Components in Critically Ill Children. Indian Journal of Pediatrics. 2010 Dec ; 77 (12): 1424-1428.