Effects of undernutrition and sex difference on skeletal muscle function in young rats.

dc.contributor.authorKrishnamurthy, Nen_US
dc.contributor.authorBalakumar, Ben_US
dc.contributor.authorThombre, D Pen_US
dc.date.accessioned1992-10-01en_US
dc.date.accessioned2009-06-01T06:54:24Z
dc.date.available1992-10-01en_US
dc.date.available2009-06-01T06:54:24Z
dc.date.issued1992-10-01en_US
dc.description.abstractThe effects of undernutrition and sex difference on skeletal muscle contractile characteristics were studied in young albino rats. The skeletal muscle (gastrocnemius) of 8 week old pups with only one-third normal food intake (undernourished group = UN group; n = 18), as compared to free fed pups (control group = cont. group; n = 16), showed prolongation of contraction time (23.6 +/- 1.0 Vs 20.9 +/- 0.8 msec, Mean +/- SE, P < 0.05) and relaxation time (31.5 +/- 1.8 Vs 22.9 +/- 1.1 msec, P < 0.001) and retention of contraction force and endurance time. In 18 week old rats the effects of sex difference in females (n = 10), as compared to males (n = 10) were prolongation of contraction time in gastrocnemius (32.2 +/- 1.5 Vs 27.8 +/- 1.5 msec, P < 0.05), less force production in gastrocnemius (668.9 +/- 48.0 Vs 895.4 +/- 93.3 g, P < 0.05) and extensor digitorum longus (20.1 +/- 3.3 Vs 29.9 +/- 2.5 g, P < 0.05) and shorter endurance time (160.8 +/- 10.2 Vs 187.2 +/- 7.1 sec, P < 0.05) in soleus. Thus, it is concluded that early undernutrition has prolonged the contraction and relaxation times of the skeletal muscles and the effect of sex difference in the early adulthood was different in different skeletal muscles.en_US
dc.description.affiliationDepartment of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.en_US
dc.identifier.citationKrishnamurthy N, Balakumar B, Thombre DP. Effects of undernutrition and sex difference on skeletal muscle function in young rats. Indian Journal of Physiology and Pharmacology. 1992 Oct; 36(4): 234-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/107746
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBody Weight --physiologyen_US
dc.subject.meshDeficiency Diseases --physiopathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFood Deprivation --physiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMuscle Contraction --physiologyen_US
dc.subject.meshMuscles --physiologyen_US
dc.subject.meshNutritional Status --physiologyen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSex Characteristicsen_US
dc.titleEffects of undernutrition and sex difference on skeletal muscle function in young rats.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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