SSPE - The continuing challenge: A study based on serological evidence from a teritary care centre in India.

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dc.contributor.authorManayani, D Jen_US
dc.contributor.authorAbraham, Men_US
dc.contributor.authorGnanamuthu, Cen_US
dc.contributor.authorSolomon, Ten_US
dc.contributor.authorAlexander, Men_US
dc.contributor.authorSridharan, Gen_US
dc.date.accessioned2002-01-28en_US
dc.date.accessioned2009-05-28T09:18:57Z
dc.date.available2002-01-28en_US
dc.date.available2009-05-28T09:18:57Z
dc.date.issued2002-01-28en_US
dc.description.abstractPURPOSE: To assess the prevalence of subacute sclerosing panencephalitis (SSPE). METHODS: In the period June 96 to December' 98 an analysis for measles virus (MV) antibody was carried out on 103 serum-CSF pairs received from patients clinically suspected of SSPE. Measles antibody was detected in an indirect immunofluorescent assay (IIF) test. RESULTS: Antibody to measles was detectable in 49 (48%) of the serum-CSF pairs tested, a diagnostic criterion for SSPE. Antibody titers ranged from 20 to 1280 in serum and neat to 32 in CSF. The serum: CSF ratio ranged from 5:1 to 80:1. Of the 49 patients diagnosed to have SSPE, 36 were males and 13 females, and the age of the patients at the time of diagnosis of SSPE ranged from 5 to 26 years. Ten of the SSPE patients gave a history of measles vaccination. CONCLUSIONS: Inadequate vaccine coverage and quality of vaccine used continue to have an impact on occurrence of SSPE.en_US
dc.description.affiliationDepartment of Clinical Virology, Christian Medical College and Hospital, Vellore - 632 004, India.en_US
dc.identifier.citationManayani DJ, Abraham M, Gnanamuthu C, Solomon T, Alexander M, Sridharan G. SSPE - The continuing challenge: A study based on serological evidence from a teritary care centre in India. Indian Journal of Medical Microbiology. 2002 Jan-Mar; 20(1): 16-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53745
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.titleSSPE - The continuing challenge: A study based on serological evidence from a teritary care centre in India.en_US
dc.typeJournal Articleen_US
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