Nebulized salbutamol (Asmasal) in Thai children with asthma: comparison of three doses.

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dc.contributor.authorVisitsuntorn, Nen_US
dc.contributor.authorWichienwattanachai, Ven_US
dc.contributor.authorVichyanond, Pen_US
dc.contributor.authorKerdsomnuk, Sen_US
dc.contributor.authorTuchinda, Men_US
dc.date.accessioned2009-05-27T17:11:47Z
dc.date.available2009-05-27T17:11:47Z
dc.date.issued1994-06-01en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractEleven moderate-to-severe asthmatic children 5-11 years of age who were in stable condition were given (randomly, double-blind) nebulized salbutamol sulfate (Asmasal) inhalation therapy at doses of 0.1, 0.2 and 0.3 mg/kg body weight on separated days. All three doses of nebulized solution resulted in clinical improvement and improvement of lung function (FEV1, FVC, PEFR and FEF25-75%). A dose of 0.3 mg/kg produced greatest improvement and longest duration of improvement in FEV1 and PEFR, but the change was statistically significant only in PEFR at 60 minutes (p < 0.05). Five children experienced mild tremors. There were no significant changes in heart rate or blood pressure at any dose. It is concluded that a nebulized solution of salbutamol sulfate at a dose of 0.1-0.3 mg/kg is useful for treatment of asthma in Thai children, with very mild side effects.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationVisitsuntorn N, Wichienwattanachai V, Vichyanond P, Kerdsomnuk S, Tuchinda M. Nebulized salbutamol (Asmasal) in Thai children with asthma: comparison of three doses. Asian Pacific Journal of Allergy and Immunology. 1994 Jun; 12(1): 7-13en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36661
dc.language.isoengen_US
dc.subject.meshAdministration, Inhalationen_US
dc.subject.meshAlbuterol --administration & dosageen_US
dc.subject.meshAsthma --drug therapyen_US
dc.subject.meshChilden_US
dc.subject.meshCross-Over Studiesen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPulmonary Ventilation --drug effectsen_US
dc.subject.meshThailanden_US
dc.titleNebulized salbutamol (Asmasal) in Thai children with asthma: comparison of three doses.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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