A study of prevalence of peripheral arterial disease in type 2 diabetes mellitus using ankle-brachial index and its correlation with coronary artery disease and its risk factors

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dc.contributor.authorSharma, R. K.en_US
dc.contributor.authorSandhu, Pashaura S.en_US
dc.contributor.authorChhabra, Ajayen_US
dc.contributor.authorSingh, Jagbiren_US
dc.contributor.authorKharbanda, Rajaten_US
dc.date.accessioned2020-11-18T09:58:40Z
dc.date.available2020-11-18T09:58:40Z
dc.date.issued2019-05
dc.description.abstractBackground: Peripheral arterial disease (PAD) is one of the macrovascular complications of type 2 diabetes mellitus (T2DM). There is significant difference in the reported prevalence of PAD and its associated risk factors between Indian and Western studies. The purpose of this study was to examine the PAD complicating T2DM, in particular the influence of PAD on the risk of CAD.Methods: Randomly selected 100 T2DM patients presented to Guru Nanak Dev hospital were included. In addition to a detailed history and physical examination, anthropometric parameters like body mass index was measured. CAD in patients was diagnosed by a history of angina, ECG changes, any past history of CAD or any treatment taken for CAD. Ankle brachial index (ABI) was measured. Data was collected systematically and analyzed according to the standard statistical methods.Results: The prevalence of PAD was 15%. CAD was present in 31%. PAD was found to be significantly correlated with age, duration of diabetes, smoking, systolic blood pressure, diastolic blood pressure, prevalence of BMI >25 kg/m2, HbA1c and serum HDL ≤40 mg%. Old age, high HbA1c level, and dyslipidaemia were found to be significant independent predictors of CAD.Conclusions: Using ABI authors found evidence of PAD in 15% patients of T2DM. The prevalence of CAD was higher in patients with PAD. So, there is definite and strong correlation between PAD and CAD. Thus, the early diagnosis of PAD should alert the clinician to a high probability of underlying CAD.en_US
dc.identifier.affiliationsDepartment of Medicine, GMC Amritsar, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, PGIMER and Dr. RML Hospital, New Delhi, Indiaen_US
dc.identifier.citationSharma R. K., Sandhu Pashaura S., Chhabra Ajay, Singh Jagbir, Kharbanda Rajat. A study of prevalence of peripheral arterial disease in type 2 diabetes mellitus using ankle-brachial index and its correlation with coronary artery disease and its risk factors. International Journal of Research in Medical Sciences. 2019 May; 7(5): 1776-1780en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211476
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20191675en_US
dc.subjectAnkle-brachial indexen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectDiabetes mellitusen_US
dc.subjectPeripheral artery diseaseen_US
dc.titleA study of prevalence of peripheral arterial disease in type 2 diabetes mellitus using ankle-brachial index and its correlation with coronary artery disease and its risk factorsen_US
dc.typeJournal Articleen_US
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