SCE Analysis In Treated And Unteated Leprosy Patients.
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Date
1999-04
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Abstract
Spontaneow sister chromatid exchange (SCE) frequency was studied in fifteen leprosy patients and twelve age matched controls. The mean SCH/cell was 10.23 + 4.1 in controls. The three untreated patients had mean SCE/cell value of 20.3 + 1.41. Among patients under treatment, five patients in initial stage of disease and treatment duration between one to nine months, the mean SCE/cell value was 29.78 + 4.244. In the seven patients with advanced stage of disease and treatment duration between 20 to 50 months, the mean SCE/cell value was 31.87 + 7.31. The results indicate a clastogenic effect of leprosy on peripheral leucocytes, which was increased due to anti-leprosy treatment.
Description
Keywords
Sister chromatid exchange, Leucocytes, Leprosy
Citation
Kaur Satbir, Sambyal Vasudha, Rai Sukhwinder Kaur. SCE Analysis In Treated And Unteated Leprosy Patients. Indian Journal of Human Genetics. 1999 Apr; 5(2): 11-13.