Study of factors affecting sarcopenia in PLHIV

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dc.contributor.authorRavi, Ken_US
dc.contributor.authorSuresh, Ren_US
dc.contributor.authorVinay, Nen_US
dc.date.accessioned2025-06-18T11:13:48Z
dc.date.available2025-06-18T11:13:48Z
dc.date.issued2025-02
dc.description.abstractBackground: This study aims to determine the frequency of sarcopenia in PLHIV and determine the factors affecting sarcopenia in PLHIV. Methods: The patients fulfilling the inclusion criteria were enrolled for the study after obtaining informed consent. Case record form was used to record relevant history. SARC-F (sluggishness, assistance in walking, rising from a chair, climbing stairs, falls) score is recorded by questionnaire. Hand grip strength and skeletal muscle mass index (SMI) were recorded. The correlation between grip strength and SMI with the duration of treatment in different regimens of HAART in PLHIV were studied. Possible factors affecting sarcopenia were determined based on history taken. All the parameters were compared between patients with and without sarcopenia. P value <0.05 was considered statistically significant. R version 4.1.2 statistical software was used for the statistical analysis. Results: Sarcopenia was more commonly found in middle aged participants, who were less adherent to therapy, had a past history of tuberculosis, consumed alcohol, followed a vegetarian diet and did not exercise regularly. Conclusion: Sarcopenia is more common in middle-aged individuals with long-term AIDS, especially those on prolonged ART. It抯 linked to non-adherence to ART, alcohol consumption, history of tuberculosis, and reduced physical activity. Strict adherence to ART, avoiding alcohol, increasing protein intake, and exercising regularly helps to combat this.en_US
dc.identifier.affiliationsDepartment of General Medicine, Bangalore Medical College Institute, Bangalore, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of General Medicine, Bangalore Medical College Institute, Bangalore, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of General Medicine, Bangalore Medical College Institute, Bangalore, Karnataka, Indiaen_US
dc.identifier.citationRavi K, Suresh R, Vinay N. Study of factors affecting sarcopenia in PLHIV. International Journal of Advances in Medicine. 2025 Feb; 12(1): 33-38en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/248367
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber1en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2349-3933.ijam20243811en_US
dc.subjectSarcopeniaen_US
dc.subjectPLHIVen_US
dc.subjectRisk factorsen_US
dc.subjectHAARTen_US
dc.titleStudy of factors affecting sarcopenia in PLHIVen_US
dc.typeJournal Articleen_US
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