Anthropometric and Pubertal Outcomes in Girls With Classical Congenital Adrenal Hyperplasia

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dc.contributor.authorKaur, Japleenen_US
dc.contributor.authorSingla, Mandeepen_US
dc.contributor.authorBhansali, Anilen_US
dc.contributor.authorBhadada, Sanjayen_US
dc.contributor.authorWalia, Ramaen_US
dc.date.accessioned2023-08-25T06:39:31Z
dc.date.available2023-08-25T06:39:31Z
dc.date.issued2022-07
dc.description.abstractObjective: To evaluate the anthropometric and pubertal outcomes, over a spectrum of treatment regimens and compliance. Methods: We reviewed records of the patients with classical CAH seen at the endocrinology clinic of a tertiary care center between 1995 and 2016. Results: 25 females were included in the study, the majority (80%) with simple virilizing variant. All patients had genital ambiguity since birth, yet 40% (10/25) presented much later with menstrual complaints. All patients received hydrocortisone, but some switched to dexamethasone (n=7) or prednisolone (n=4). 7/9 (77.9%) girls who achieved target height, were on hydrocortisone. Menarche occurred with corticosteroid treatment in 60% (15/25) patients at a median (IQR) age of 16 (12-22) years. Conclusion: Hydrocortisone seems to have a beneficial effect on linear growth. Once target height is achieved, dexamethasone may be considered as an alternative.en_US
dc.identifier.affiliationsDepartments of Obstetrics and Gynecologyen_US
dc.identifier.affiliationsEndocrinology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh.en_US
dc.identifier.citationKaur Japleen, Singla Mandeep, Bhansali Anil, Bhadada Sanjay, Walia Rama. Anthropometric and Pubertal Outcomes in Girls With Classical Congenital Adrenal Hyperplasia. Indian Pediatrics. 2022 Jul; 59(7): 535-538en_US
dc.identifier.issn0079-6061
dc.identifier.issn0974-7559
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/225349
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber7en_US
dc.relation.volume59en_US
dc.source.urihttps://indianpediatrics.net/july2022/535.pdfen_US
dc.subjectDexamethasoneen_US
dc.subjectHydrocortisoneen_US
dc.subjectPrednisoloneen_US
dc.subject21?-hydroxylase deficiencyen_US
dc.subjectPubertyen_US
dc.titleAnthropometric and Pubertal Outcomes in Girls With Classical Congenital Adrenal Hyperplasiaen_US
dc.typeJournal Articleen_US
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