Palliative surgical bypass versus percutaneous transhepatic biliary drainage on unresectable hilar cholangiocarcinoma.

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dc.contributor.authorWongkonkitsin, Narongchaien_US
dc.contributor.authorPhugkhem, Akeen_US
dc.contributor.authorJenwitheesuk, Kriangsaken_US
dc.contributor.authorSaeseow, O-Turen_US
dc.contributor.authorBhudhisawasdi, Vajarabhongsaen_US
dc.date.accessioned2009-05-27T21:05:30Z
dc.date.available2009-05-27T21:05:30Z
dc.date.issued2006-11-09en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To compare the survival probability of unresectable hilar cholangiocarcinoma patients who have been managed by palliative surgical bypass versus percutaneous transhepatic biliary drainage (PTBD). MATERIAL AND METHOD: A historical (retrospective) cohort study was performed by retrospective and prospective data collection. From January 1, 2000 to December 31, 2002, all unresectable hilar cholangiocarcinoma patients who received only one type of palliative surgical bypass or PTBD in Srinagarind Hospital, Khon Kaen University were included in the present study. The patients were followed until December 31, 2004. Survival analysis was completed for all of the patients. STATISTIC ANALYSIS: Survival analysis was analyzed with the Kaplan-Meier method, Cox regression analysis, and Log-rank test. A p-value of less than 0.05 was considered significant. RESULTS: During the study period, 83 patients were included. Palliative surgical bypass was performed in 42 patients and PTBD was performed in 41 patients. Demographic data, peri-operative complication rate, and late complication rate were comparable. The median survival time of the palliative surgical bypass group was 160 days,(95% CI: 85.33, 234.67) and 82 days (95% CI: 29.76, 134.24)for PTBD group. Comparing survival experience by Log-rank test gave statistical significant diference (p = 0.0276). Hazard ratio was 0.599 (p = 0.03) CONCLUSION: Survival rate of the palliative surgical bypass group was higher than the PTBD group. The survival rate of both groups was comparable to previous reports.en_US
dc.description.affiliationGeneral Surgery 3 Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. narwon@kku.ac.then_US
dc.identifier.citationWongkonkitsin N, Phugkhem A, Jenwitheesuk K, Saeseow OT, Bhudhisawasdi V. Palliative surgical bypass versus percutaneous transhepatic biliary drainage on unresectable hilar cholangiocarcinoma. Journal of the Medical Association of Thailand. 2006 Nov; 89(11): 1890-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/44178
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshBile Duct Neoplasms --mortalityen_US
dc.subject.meshBile Ducts, Intrahepatic --surgeryen_US
dc.subject.meshBiliary Tract Surgical Procedures --methodsen_US
dc.subject.meshCholangiocarcinoma --mortalityen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshDrainage --methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPalliative Care --methodsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSurvival Rateen_US
dc.titlePalliative surgical bypass versus percutaneous transhepatic biliary drainage on unresectable hilar cholangiocarcinoma.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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