Per rectal diazepam therapy in convulsive disorders.

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dc.contributor.authorKalra, Aen_US
dc.contributor.authorChaturvedi, Nen_US
dc.contributor.authorVashishtha, V Men_US
dc.contributor.authorDube, K Nen_US
dc.contributor.authorKalra, Ken_US
dc.date.accessioned1992-08-01en_US
dc.date.accessioned2009-05-27T05:08:34Z
dc.date.available1992-08-01en_US
dc.date.available2009-05-27T05:08:34Z
dc.date.issued1992-08-01en_US
dc.description.abstractOne hundred and twenty children with persistent convulsions (lasting > or = 10 min) were treated with per rectal diazepam (dosage: 0.2 to 0.7 mg/kg/dose). Another group of 100 age matched children with convulsions, along with those who did not respond to rectal therapy were given intravenous diazepam in a dosage of 0.2 to 0.3 mg/kg/dose. Rectal treatment was effective in 80.83% cases while intravenous diazepam was effective in 90% cases which is statistically just significant (p < 0.05). No significant difference was observed in the efficacy of two routes of administration in controlling convulsions of different clinical types and various etiological groups (p < 0.05), except for primary generalized type where intravenous route was more effective than the rectal one (p < 0.05). No significant side-effect was observed with rectal therapy. Among the 23 (19.17%) children in whom rectal therapy failed, 12 (10%) responded to intravenous diazepam while the remaining 11 (9.17%) cases were resistant to both routes of administration.en_US
dc.description.affiliationDepartment of Pediatrics, S.N. Medical College, Agra.en_US
dc.identifier.citationKalra A, Chaturvedi N, Vashishtha VM, Dube KN, Kalra K. Per rectal diazepam therapy in convulsive disorders. Indian Pediatrics. 1992 Aug; 29(8): 975-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/8552
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAdministration, Rectalen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDiazepam --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInjections, Intravenousen_US
dc.subject.meshMaleen_US
dc.subject.meshSeizures --drug therapyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titlePer rectal diazepam therapy in convulsive disorders.en_US
dc.typeJournal Articleen_US
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