Echocardiographic evaluation of ventricular dyssynchrony in patients with left bundle branch block.

Simple item page
dc.contributor.authorRoshan, Johnen_US
dc.contributor.authorPati, Purendra Kumaren_US
dc.contributor.authorJose, Jacob Ven_US
dc.date.accessioned2008-11-12en_US
dc.date.accessioned2009-05-27T04:27:13Z
dc.date.available2008-11-12en_US
dc.date.available2009-05-27T04:27:13Z
dc.date.issued2008-11-12en_US
dc.description.abstractOBJECTIVE: To test whether patients with left bundle branch block (LBBB) and low ejection fraction (EF) have greater dyssynchrony than those with LBBB and normal LV systolic function. METHODS: From a group of patients with LBBB, 38 patients with low EF (<50%) and 31 with normal LV systolic function (EF > or = 50%), all comparable in age and sex underwent standard Doppler echo, ECG and tissue Doppler imaging (TDI). The precontraction time (PCTm) was calculated as an index of myocardial systolic activation in 5 different basal myocardial segments (LV anterior, inferior, septal, lateral walls and RV lateral wall). Intraventricular systolic dyssynchrony was analyzed by difference of PCTm in different LV myocardial segments. Interventricular activation delay was calculated by the difference of PCTm between the most delayed LV segment and RV lateral wall. RESULTS: Patients with low LV EF showed increased QRS duration, intraventricular delay (p = 0.03) and interventricular dyssynchrony (p = 0.006). Patients with normal EF also had evidence of some dyssynchrony. The LV basal lateral segment was significantly delayed when compared to all other segments in the low EF group. The PCTm was greater for those with low EF when compared to the normal EF group. CONCLUSIONS: All patients with LBBB on baseline ECG had some degree of cardiac dyssynchrony; those with lower EF had more dyssynchrony. TDI is an effective non-invasive technique for assessing the severity of regional delay in activation of ventricular walls in patients with LBBB.en_US
dc.description.affiliationDepartment of Cardiology, Christian Medical College, Vellore, Tamil Nadu, India. john_roshan@coolgoose.comen_US
dc.identifier.citationRoshan J, Pati PK, Jose JV. Echocardiographic evaluation of ventricular dyssynchrony in patients with left bundle branch block. Indian Heart Journal. 2008 Nov-Dec; 60(6): 567-73en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/5392
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshBundle-Branch Block --physiopathologyen_US
dc.subject.meshDiastoleen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshStroke Volumeen_US
dc.subject.meshSystoleen_US
dc.subject.meshVentricular Dysfunction, Left --physiopathologyen_US
dc.titleEchocardiographic evaluation of ventricular dyssynchrony in patients with left bundle branch block.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Heart Journal