Intralesional Bleomycin For Lymphangioma: An Effective Alternative Non-Surgical Therapy
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Date
2019-01
Journal Title
Journal ISSN
Volume Title
Publisher
International Research Organization for Life & Health Sciences (IROLHS)
Abstract
Introduction: Conventionally, lymphangiomas have been managed by surgical excision which range from simple excision toextensive compartmental exenteration.With the advent of the usefulness of sclerotherapy, especially bleomycin, management ofextensive lymphangiomas which are hitherto considered inoperable cases has become very comfortable for patient and surgeon.Materials and Methods: A total of 28 patients were included in the study. Neck was the most common site of involvementfollowed by axilla; groin was involved in two cases. Injection bleomycin was reconstituted and diluted, a dose of 0.5 IU/Kg injectedintralesionally after aspirating an equal volume of fluid. Compression bandage was applied for 24 h. Cases were reviewed after3 weeks for assessing clinical and serological response.Results: Significant reduction of mass was noted in 68% of cases (n = 19). Surgery was required in 7% (n = 2), completeregression of mass was noted in the remaining 25% (n = 7) cases.Conclusion: This modality of treatment may be used safely as primary modality of treatment for select group of patients.
Description
Keywords
Bleomycin, Lymphangioma, Sclerotherapy
Citation
Prasad Damisetti Kalyan Ravi, Reddy Jeeru Bhaskar. Intralesional Bleomycin For Lymphangioma: An Effective Alternative Non-Surgical Therapy. International Journal of Scientific Study. 2019 Jan; 6(10): 82-83