Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience.

Simple item page
dc.contributor.authorKalogeridi, Maria-Aggelikien_US
dc.contributor.authorGeorgolopoulou, Paraskevien_US
dc.contributor.authorKouloulias, Vassilisen_US
dc.contributor.authorKouvaris, Johnen_US
dc.contributor.authorPissakas, Georgeen_US
dc.date.accessioned2009-01-19en_US
dc.date.accessioned2009-06-01T16:26:20Z
dc.date.available2009-01-19en_US
dc.date.available2009-06-01T16:26:20Z
dc.date.issued2009-01-19en_US
dc.description.abstractPURPOSE: To estimate the value of LINAC-based stereotactic radiosurgery (SRS) for the long-term local control of unilateral acoustic neuromas. MATERIALS AND METHODS: Twenty patients (median age 66; range 57-80 years) with unilateral acoustic neuroma underwent LINAC-based SRS from May 2000 through June 2004 with a dose of 11-12 Gy. The follow-up period ranged from 36 to 84 months (median follow-up period: 55 months). Before SRS none of the patients had useful hearing. The follow-up consisted of repeat imaging studies and clinical examination for assessment of facial and trigeminal nerve function at 6-month intervals for the first year and yearly thereafter. RESULTS: Eleven tumors (58%) decreased in size and eight (42%) remained stable. One tumor showed a minor increase in size on the MRI done 6 months after SRS in comparison with the pretreatment MRI; however, a subsequent decrease was noticed on the next radiographic assessment and the tumor remained stable from then on. None of the tumors increased in size in the long-term follow-up, thus giving an overall growth control of 100% for the patients in this study. None of the patients had useful hearing before SRS, so hearing level was not assessed during follow-up. No patient developed new, permanent facial or trigeminal neuropathy. CONCLUSION: LINAC-based SRS with 11-12 Gy provides excellent tumor control in acoustic neuroma and has low toxicity even after long-term follow-up.en_US
dc.description.affiliationRadiotherapy Unit, Medical School, National University of Athens, Greece. ma_kalogeridi@yahoo.comen_US
dc.identifier.citationKalogeridi MA, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G. Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience. Journal of Cancer Research and Therapeutics. 2009 Jan-Mar; 5(1): 8-13en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/111552
dc.language.isoengen_US
dc.source.urihttps://www.cancerjournal.neten_US
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshGreece
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNeuroma, Acoustic --surgery
dc.subject.meshPostoperative Complications --epidemiology
dc.subject.meshRadiosurgery --adverse effects
dc.subject.meshTreatment Outcome
dc.titleLong-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of Cancer Research and Therapeutics