Platelet adhesiveness in diabetes mellitus with relation to treatment.

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dc.contributor.authorSamal, K Ken_US
dc.contributor.authorSahu, C Sen_US
dc.contributor.authorNanda, R Cen_US
dc.date.accessioned1991-06-01en_US
dc.date.accessioned2009-05-31T08:34:49Z
dc.date.available1991-06-01en_US
dc.date.available2009-05-31T08:34:49Z
dc.date.issued1991-06-01en_US
dc.description.abstractTo determine whether diabetes mellitus alters the function of platelets, a study on platelet adhesiveness in 30 controls and 75 newly diagnosed diabetics (25 cases of type-1 and 50 cases of type-II) before and after treatment was undertaken. The platelet adhesiveness was 68.83 +/- 6.09% (mean + SD) in type-I diabetics, 72.43 +/- 6.10% in type-II diabetics and 56.31 +/- 9.62% in controls (p less than 0.001 for all comparisons). In complicated diabetics (54 cases) the platelet adhesiveness was 72.33 +/- 5.99% and in uncomplicated diabetics (21 cases) it was 67.33 +/- 5.82% (p less than 0.05). Platelet adhesiveness was significantly reduced after treatment (with insulin it was 62.12 +/- 7.46%, with phenformin 62.10 +/- 8.63 and with tolbutamide 67.12 +/- 7.97%) when compared with pretreatment values. Platelet adhesiveness had no significant correlation with blood sugar and serum cholesterol levels. These results support the concept that platelet adhesiveness is high in diabetes mellitus and is reduced with control of diabetic state after treatment.en_US
dc.description.affiliationDepartment of Medicine, VSS Medical College, Burla.en_US
dc.identifier.citationSamal KK, Sahu CS, Nanda RC. Platelet adhesiveness in diabetes mellitus with relation to treatment. Journal of the Indian Medical Association. 1991 Jun; 89(6): 155-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/97854
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdulten_US
dc.subject.meshDiabetes Mellitus, Type 1 --blooden_US
dc.subject.meshDiabetes Mellitus, Type 2 --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypoglycemic Agents --therapeutic useen_US
dc.subject.meshMaleen_US
dc.subject.meshPlatelet Adhesiveness --drug effectsen_US
dc.titlePlatelet adhesiveness in diabetes mellitus with relation to treatment.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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