Retinopathy of prematurity: incidence and risk factors.

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dc.contributor.authorRekha, Sen_US
dc.contributor.authorBattu, R Ren_US
dc.date.accessioned1996-12-01en_US
dc.date.accessioned2009-05-27T05:03:47Z
dc.date.available1996-12-01en_US
dc.date.available2009-05-27T05:03:47Z
dc.date.issued1996-12-01en_US
dc.description.abstractOBJECTIVE: To determine the incidence of Retinopathy of Prematurity (ROP) in high risk babies admitted to the neonatal unit and to study risk factors for it's development. DESIGN: Prospective cohort study. SETTING: Level II Neonatal Intensive Care Unit. SUBJECTS: 100 babies admitted to the neonatal unit during a 4 year period who were below 1500 g or whose gestation was < or = 34 weeks. METHODS: Examination of the eye was done in the neonatal unit or in the neonatal follow up clinic by an Ophthalmologist by indirect Ophthalmoscopy at 4-6 weeks postnatal age. RESULTS: The incidence of ROP was 46%. Of the 100 babies screened, 21 had stage I, 14 had stage II, 8 had stage III and 3 had stages IV and V. The incidence of ROP was 73.3% among < 1000 g babies and 47.3% among < 1500 g babies. The incidence of ROP among 28-29 weeks, 30-31 weeks and 32-33 weeks babies was 83%, 60% and 50%, respectively. The maximum stage of ROP developed between 37-42 weeks post conceptional age in 69% subjects. On univariate analysis, gestation < or = 32 weeks, anemia, Blood transfusions, apnea and exposure to oxygen significantly increased the risk of developing ROP. On multivariate logistic regression analysis, anemia and duration of oxygen therapy were the significant independent predictors of development of ROP. Nine of the 46 babies underwent cryotherapy for threshold ROP. CONCLUSION: The incidence of ROP among high risk babies is significant and duration of oxygen therapy and anemia are independent factors predicting the development of ROP. All high risk babies should be screened for ROP. Cryotherapy is a relatively simple procedure which can be done in the neonatal unit.en_US
dc.description.affiliationDepartment of Pediatrics, St. John's Medical College Hospital, Bangalore.en_US
dc.identifier.citationRekha S, Battu RR. Retinopathy of prematurity: incidence and risk factors. Indian Pediatrics. 1996 Dec; 33(12): 999-1003en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/7834
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAnalysis of Varianceen_US
dc.subject.meshAnemia --epidemiologyen_US
dc.subject.meshApnea --epidemiologyen_US
dc.subject.meshBlood Transfusion --statistics & numerical dataen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshCryosurgeryen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshForecastingen_US
dc.subject.meshGestational Ageen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Low Birth Weighten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Prematureen_US
dc.subject.meshInfant, Small for Gestational Ageen_US
dc.subject.meshInfant, Very Low Birth Weighten_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshOphthalmoscopyen_US
dc.subject.meshOxygen Inhalation Therapy --statistics & numerical dataen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRetinopathy of Prematurity --classificationen_US
dc.subject.meshRisk Factorsen_US
dc.titleRetinopathy of prematurity: incidence and risk factors.en_US
dc.typeJournal Articleen_US
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