Aetiology and prognostic factors in hepatic failure in central India.

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dc.contributor.authorJaiswal, S Ben_US
dc.contributor.authorChitnis, D Sen_US
dc.contributor.authorAsolkar, M Ven_US
dc.contributor.authorNaik, Gen_US
dc.contributor.authorArtwani, K Ken_US
dc.date.accessioned1996-10-01en_US
dc.date.accessioned2009-06-04T04:49:28Z
dc.date.available1996-10-01en_US
dc.date.available2009-06-04T04:49:28Z
dc.date.issued1996-10-01en_US
dc.description.abstractThe present study was undertaken to establish the aetiology and prognostic factors of liver failure in central India. Of the 122 cases of hepatic failure 95 (78%), 19 (15.5%) and 8 (6.5%) were labelled as fulminant hepatic failure (FHF), chronic hepatic failure (CHF) and subacute hepatic failure (SAHF) respectively. Hepatitis E virus (HEV) and hepatitis B virus (HBV) were aetiological agents amongst 41% (n = 39) and 37% (n = 35) patients with FHF respectively. Mixed infection among such cases even though observed was infrequent and 15% (n = 14) of FHF did not have any serological markers. They were presumed to be due to non A-E viral infection. Thirty-one (33%) of the FHF patients were pregnant and 29 (94%) of them were due to HEV. Amongst patients with SAHF and CHF, HBV and HCV were important aetiological agents. The static prognostic risk factors noted in the present study are age above 40 years, presence of identifiable viral aetiology (A to E), alcoholic status in males and pregnancy particularly in the third trimester or postpartum state. Among the dynamic factors, bilirubin level above 20 mg/dl and prothrombin time over 20 seconds appeared to be the risk factors.en_US
dc.description.affiliationDepartment of Microbiology and Immunology, Choithram Hospital and Research Centre, Indore, India.en_US
dc.identifier.citationJaiswal SB, Chitnis DS, Asolkar MV, Naik G, Artwani KK. Aetiology and prognostic factors in hepatic failure in central India. Tropical Gastroenterology. 1996 Oct-Dec; 17(4): 217-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/125171
dc.language.isoengen_US
dc.source.urihttps://www.tropicalgastro.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLiver Failure --diagnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Infectious --diagnosisen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.titleAetiology and prognostic factors in hepatic failure in central India.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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