Development, Cognition, Adaptive Function and Maladaptive Behavior in HIV-infected and HIV-exposed Uninfected Children Aged 2-9 Years

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dc.contributor.authorMukherjee, Sharmila Banerjeeen_US
dc.contributor.authorDevamare, Shilpaen_US
dc.contributor.authorSeth, Anjuen_US
dc.contributor.authorSapra, Savitaen_US
dc.date.accessioned2020-04-23T07:44:29Z
dc.date.available2020-04-23T07:44:29Z
dc.date.issued2019-11
dc.description.abstractObjectives: To compare development/cognition, adaptive function and maladaptive behaviorof HIV-infected and HIV-exposed uninfected children between 2 to 9 years with HIV-uninfected controls. Methods: This hospital-based cross-sectional study was conductedfrom November, 2013 to March, 2015. 50 seropositive HIV-infected, 25 HIV-exposeduninfected and 25 HIV-uninfected children between 2 to 9 years were administeredDevelopmental Profile 3, Vineland Adaptive Behavior Scale 2, and Child Behavior Checklistfor assessing development, adaptive function and maladaptive behaviour, respectively.Additional data were obtained by history, examination and review of records. Results:Significant developmental/cognitive impairment was observed in 38 (76%), 16 (64%) and 6(24%) HIV-infected, HIV-exposed uninfected, and HIV-uninfected children, respectively.Significant impairment in adaptive function was found in 12 (24%) and 2 (8%) HIV-infectedand HIV-exposed uninfected children, respectively. Maladaptive behavior was not seen in anygroup. Conclusions: High magnitude of impaired development/cognition and adaptivefunction in HIV-exposed and HIV-infected children warrants assessment of these domainsduring follow-up of these children, and incorporation of interventions for these deficits instandard care for this group.en_US
dc.identifier.affiliationsDepartments of Pediatrics, Lady Hardinge Medical College and associated hospitalsen_US
dc.identifier.affiliationsAll India Institute of MedicalSciences; New Delhi, India.en_US
dc.identifier.citationMukherjee Sharmila Banerjee, Devamare Shilpa, Seth Anju, Sapra Savita. Development, Cognition, Adaptive Function and Maladaptive Behavior in HIV-infected and HIV-exposed Uninfected Children Aged 2-9 Years. Indian Pediatrics. 2019 Nov; 56(11): 933-938en_US
dc.identifier.issn0974-7559
dc.identifier.issn0019-6061
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199424
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber11en_US
dc.relation.volume56en_US
dc.source.urihttps://www.indianpediatrics.net/nov2019/933.pdfen_US
dc.subjectAcquired immunodeficiency disorderen_US
dc.subjectDevelopmental delayen_US
dc.subjectNeurocognition,Outcomeen_US
dc.titleDevelopment, Cognition, Adaptive Function and Maladaptive Behavior in HIV-infected and HIV-exposed Uninfected Children Aged 2-9 Yearsen_US
dc.typeJournal Articleen_US
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