Carbon monoxide poisoning.

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dc.contributor.authorMehta, S Ren_US
dc.contributor.authorNiyogi, Men_US
dc.contributor.authorKasthuri, A Sen_US
dc.contributor.authorDubal, Uen_US
dc.contributor.authorBindra, Sen_US
dc.contributor.authorPrasad, Den_US
dc.contributor.authorLahiri, A Ken_US
dc.date.accessioned2001-06-05en_US
dc.date.accessioned2009-05-30T19:51:41Z
dc.date.available2001-06-05en_US
dc.date.available2009-05-30T19:51:41Z
dc.date.issued2001-06-05en_US
dc.description.abstractOBJECTIVES: We studied the clinical profile and autopsy findings of carbon monoxide (CO) poisoning encountered at a hospital located at the altitude of 5,000 ft above mean sea level. METHODS: Clinical and postmortem findings in 25 and 15 cases of accidental CO poisoning respectively were evaluated. The diagnosis was made on circumstantial evidences, definite history of "Bukhari" burning and positive Kunkel's test for carboxyhaemoglobin (COHb). Detailed routine investigations including pulse oxymetry, X-ray chest and electrocardiographical monitoring was carried out in all the 25 patients. Oxygen (100%) via an endotracheal tube in all the comatosed patients and by conventional non-rebreathing plastic face masks was the mainstay of treatment. All patients were monitored and followed up for any delayed neurological sequelae. RESULTS: Most of the patients were young adults and the duration of exposure varied between three to eight hours. The initial diagnosis was stroke in three, seizure in one, encephalitis in two and ischaemic heart disease (IHD) in four. Neurological and respiratory signs and symptoms were noted in 19 and 18 of 25 patients respectively. SPO2 measured by pulse oxymetry was normal in all cases. ECG was suggestive of IHD in four patients. No delayed neurological sequelae was noted in any patients. Autopsy revealed deep red discoloration of skin and serous membranes in 80%, pulmonary oedema in 100% and cerebral oedema with widespread multiple pin point haemorrhages mainly in thalamus and globus pallidus in 40%. CONCLUSION: A high level of suspicion and routine history about the kind of indoor heating, specially in cold climate areas during winter will help in early diagnosis and decrease the incidence of misdiagnosis of CO poisoning. Oxygen (100%) or hyperbaric oxygen, if available should be administered without waiting for COHb levels to decrease morbidity and mortality.en_US
dc.description.affiliationDepartment of Medicine, AFMC, Pune.en_US
dc.identifier.citationMehta SR, Niyogi M, Kasthuri AS, Dubal U, Bindra S, Prasad D, Lahiri AK. Carbon monoxide poisoning. Journal of the Association of Physicians of India. 2001 Jun; 49(): 622-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/87170
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAutopsyen_US
dc.subject.meshCarbon Monoxide Poisoning --complicationsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.titleCarbon monoxide poisoning.en_US
dc.typeJournal Articleen_US
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