Study of outcome of the treatment with intravenous iron sucrose in moderately anaemic pregnant women

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dc.contributor.authorKalimuthu, Kohilaen_US
dc.contributor.authorAvudaithangam, Vanushaen_US
dc.date.accessioned2020-10-16T07:58:57Z
dc.date.available2020-10-16T07:58:57Z
dc.date.issued2019-09
dc.description.abstractBackground: Moderate anaemia seen in about 15-20% of pregnant women. Iron sucrose complex which is used intravenously for the correction of Iron deficiency anaemia. The drug has been able to raise the haemoglobin to satisfactory level when used in moderately anaemic iron deficient pregnant women. The objective of this study was to study the improvement of Hb% after treatment with intravenous Iron sucrose complex in moderately anaemic pregnant women belonging to 24-32 weeks of gestational age.Methods: 50 antenatal patients between gestational age 24-32 weeks with hemoglobin between 8-9.5g/dl were selected and included in this study. They were subjected to blood hemoglobin estimation, hematocrit and peripheral smear study. In each infusion, the maximum total dose administered was 200 mg iron sucrose in 100 ml of normal saline, slow IV infused over 30 minutes. Monitoring was done throughout the infusion to observe for any side effects.Results: Mean hemoglobin among the 50 patients before starting the therapy was 8.172g/dl and the mean hemoglobin at the end of one month of completing the therapy was 11.066g/dl. The rise in mean hemoglobin i.e. the difference in the mean hemoglobin before and after treatment was 2.894g/dl. The p value is 0.0001 which is statistically significant. The mean hematocrit of the 50 patients studied before starting the treatment was 26.772% with a standard deviation of 1.914. The mean hematocrit after completing the therapy was 33.872% with a standard deviation of 1.321. The difference in the mean hematocrit was 7.100% with a p value of 0.0001 which is statistically significant.Conclusions: Intravenous iron sucrose complex is well tolerated and highly efficacious in improving hemoglobin, hematocrit in the treatment of iron deficiency anaemia in antenatal women.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.citationKalimuthu Kohila, Avudaithangam Vanusha. Study of outcome of the treatment with intravenous iron sucrose in moderately anaemic pregnant women. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Sep; 8(9): 3480-3484en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207063
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20193695en_US
dc.subjectHaemoglobinen_US
dc.subjectHematocriten_US
dc.subjectIntravenous iron sucroseen_US
dc.subjectIron deficiency anaemiaen_US
dc.subjectIron sucrose complexen_US
dc.subjectModerate anaemiaen_US
dc.titleStudy of outcome of the treatment with intravenous iron sucrose in moderately anaemic pregnant womenen_US
dc.typeJournal Articleen_US
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