A case of herpes simplex keratouveitis diagnosed by real time polymerase chain reaction.
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Date
2015-11
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Abstract
A 59‑year‑old Asian Indian male presented with complaints of
left eye blurring of vision associated with on and off episodes
eye pain and redness since last 4 months. On examination,
his best corrected visual acuity in the right eye was 6/15, N12
and left eye counting finger at 2 m, <N36. Anterior segment
examination of the left eye revealed circumciliary congestion,
corneal edema, mutton fat pigmented keratic precipitates,
and dilated pupil with complicated cataract [Fig. 1a and b].
Intraocular pressure (IOP) in the right eye was 18 and left eye
48 mmHg. On the basis of history and clinical examination,
a probable diagnosis of viral anterior granulomatous
keratouveitis was made. The patient was started on topical
prednisolone, homatropine, and empirical tablet acyclovir.
Patient was also advised tablet. Acetazolamide, topical
antiglaucoma medications (timolol and brinzolamide) in left
eye to control IOP. Anterior chamber tap was done in left eye
for real time polymerase chain reaction (RT‑PCR) for herpes
simplex virus (HSV). RT‑PCR report was positive for HSV
[Fig. 2a and b]. The patient was started with T. valacyclovir
1 g 3 times and tapering dose of topical prednisolone. The
patient is on follow‑up and responding well to the treatment.
Description
Keywords
Herpes simplex, polymerase chain reaction, uveitis
Citation
Gondchawar Ankush, Biswas Jyotirmay, Murali Sowmiya, Mayura Lavanya, Eawaran Priya. A case of herpes simplex keratouveitis diagnosed by real time polymerase chain reaction. Indian Journal of Ophthalmology. 2015 Nov; 63(11): 854-855.