Neuromuscular weakness in critically ill.

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dc.contributor.authorKhilnani, G Cen_US
dc.contributor.authorBansal, Ren_US
dc.date.accessioned2004-02-20en_US
dc.date.accessioned2009-05-30T22:33:25Z
dc.date.available2004-02-20en_US
dc.date.available2009-05-30T22:33:25Z
dc.date.issued2004-02-20en_US
dc.description42 references.en_US
dc.description.abstractNeuromuscular weakness in critically ill has been increasingly reported in the recent years. Occasionally it may lead to difficulty in weaning the patients from mechanical ventilation, which is difficult to diagnose clinically. Though in well-planned studies the incidence has been reported to be high, the diagnosis is often missed due to the presence of various confounding factors in the form of drug effects, underlying disorder and coexisting abnormalities of the central nervous system. A high index of suspicion with detailed neurological and electrophysiological examination is required for an early and accurate diagnosis. A wide spectrum of disorders and drugs can be responsible for the critical illness neuromuscular abnormality. The most frequent and defined disorders include; critical illness polyneuropathy (CIP) which is characterized by a sensorimotor reversible polyneuropathy presenting as distal symmetrical weakness with loss of deep tendon reflexes. Acute myopathy is another important disorder in this group which usually presents with quadriplegia often related to steroid use. Persistent blockade of neuromuscular junction is also defined in critically ill patients. It is, therefore, important to understand these disorders and their implications in the management of these patients. Some of the conditions require prolonged neuro-rehabilitation. The various acquired disorders leading to neuromuscular abnormalities in critical care, and their diagnosis and management are discussed.en_US
dc.description.affiliationDepartment of Medicine, All India Institute of Medical Science, New-Delhi-110 029.en_US
dc.identifier.citationKhilnani GC, Bansal R. Neuromuscular weakness in critically ill. Journal of the Association of Physicians of India. 2004 Feb; 52(): 131-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/89633
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshCritical Illness --mortalityen_US
dc.subject.meshElectromyographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshIntensive Care Unitsen_US
dc.subject.meshMaleen_US
dc.subject.meshMuscular Atrophy --diagnosisen_US
dc.subject.meshPolyneuropathies --diagnosisen_US
dc.subject.meshRespiration, Artificialen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSurvival Analysisen_US
dc.titleNeuromuscular weakness in critically ill.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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