L-carnitine in Beta Thalassemia.
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Date
2010-02
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Abstract
This study was conducted to determine L-carnitine levels in regularly transfused
and chelated beta thalassemia patients (n=40; mean age, 17.5±5.0 years).Ten age
matched controls were also studied. The mean L-carnitine level in thalassemic
patients was 23.71±7.3μM as compared to control 29.26±2.37μM (P<0.0001).
Mean Carnitine was significantly lower (P=0.037) in those with ferritin greater than
2000ng/dL (22.80±6.97μM) in comparison to those with ferritin less than 2000ng/
dL (30.1±7.77μM). Although Carnitine levels in non vegetarians was higher (26.91
±8.4μM) than in vegetarians (22.34±6.55μM), this difference was not statistically
significant (P=0.072). We conclude that L-carnitine levels were found to be lower
in thalassemics as compared to age matched controls.
Description
Keywords
Carnitine, Ferritin, Thalassemia
Citation
Merchant Rashid, Jain Abhay, Udani Amish, Puri Vipla, Kotian Mallika. L-carnitine in Beta Thalassemia. Indian Pediatrics. 2010 Feb; 47(2): 165-167.