Screening of antimicrobial activity of herbal extract of Embelia Basal, Chlorhexidine & Amoxicillin against salivary microflora of mixed dentition age group.
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Date
2012-01
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Abstract
The word, Ayurveda in Sanskrit roughly means the “science or knowledge of life.”
Other Ayurvedic experts however, contend that Ayurveda is even more accurately translated as
the “science or knowledge of longevity.” As such, it focuses on comprehensively addressing
the body and preventing disease by reestablishing equilibrium. When balance is achieved,
longevity – living a long, healthy, active and productive life – can be obtained(Frawley
D.1989., Svoboda RE 1989). Medicinal plants represent a rich source of antimicrobial agents.
Plants are used medicinally in the different countries and are a source of many potent and
powerful drugs(Srivastava J et al., 1996). In this study the Antimicrobial activity of ‘Embelia
Basal’ in acetone extracts were compared with Chlorhexidine and Amoxicillin 125mg and
Amoxicillin 250mg against human salivary microfloraat different concentrations. The
antimicrobial activity was assisted by measuring the inhibition zones by well diffusion
method. Saliva was collected from children of age group 6-12 years having DMFT value four
or above four. Ten salivary samples were tested for antimicrobial property to determine the
Minimum Inhibition Concentration in order to increase the reliability and precision of the
study. The results confirmed the antimicrobial potential of ‘Embeiia Basal’ plant at different
concentrations in acetone extracts are comparable with chlorhexidine and Amoxicillin and can
be used as preventive and therapeutic measure in dentistry.
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Keywords
Embelia Basal, Chlorhexidine, Amoxicillin
Citation
Deshpande Rahul R, Kulkarni Ankur, Jadhav Megha, Mahajan Priyanka, Varghese Vivian, Gaikwad Sucheta A, Deshpande Nirmala R. Screening of antimicrobial activity of herbal extract of Embelia Basal, Chlorhexidine & Amoxicillin against salivary microflora of mixed dentition age group. Journal of Applied Pharmaceutical Science. 2012 Jan; 2(1): 70-72.