A comparative clinical study of sisomicin cream versus mupirocin ointment in pyodermas.

dc.contributor.authorOberai, Chetanen_US
dc.contributor.authorShailendra, Sen_US
dc.contributor.authorDalal, Darchanen_US
dc.contributor.authorPatil, D Jen_US
dc.contributor.authorPatil, Rajshrien_US
dc.contributor.authorUmrigar, Deepaken_US
dc.contributor.authorChowdhury, Sandipen_US
dc.date.accessioned2009-05-28T08:47:04Z
dc.date.available2009-05-28T08:47:04Z
dc.date.issued2002-03-28en_US
dc.description.abstractThis study was designed to compare the efficacy and safety of sisomicin cream (0.1%) or mupirocin ointment (2%) in the treatment of primary or secondary pyodermas requiring topical antibiotic therapy alone. In the evaluable patients (n=290), impetigo was the commonest clinical condition reported. Staphylococcus aureus was the commonest pathogen isolated from the lesions. Both sisomicin and mupirocin treatments produced a steady improvement in the scores of erythema, oedema, vesiculation, pustulation, crusting and scaling but the improvement produced by sisomicin was quicker and more pronounced. The percentage of patients with complete clearing of all lesions was also higher with sisomicin than with mupirocin on days 4, 8 and 14. Patients subjectively rated the sisomicin formulation as excellent in 75% of cases as against 59% with mupirocin. Sisomicin and mupirocin are effective and safe in the management of pyodermas; however sisomicin therapy resulted in faster and greater relief of signs and symptoms.en_US
dc.description.affiliationDept. of Skin, STD & Leprosy, Grant Medical College & Sir J. J. Group of Hospitals J. J. Road, Byculla, Mumbai, India.en_US
dc.identifier.citationOberai C, Shailendra S, Dalal D, Patil DJ, Patil R, Umrigar D, Chowdhury S. A comparative clinical study of sisomicin cream versus mupirocin ointment in pyodermas. Indian Journal of Dermatology, Venereology and Leprology. 2002 Mar-Apr; 68(2): 78-81en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53119
dc.language.isoengen_US
dc.source.urihttps://www.ijdvl.comen_US
dc.titleA comparative clinical study of sisomicin cream versus mupirocin ointment in pyodermas.en_US
dc.typeJournal Articleen_US
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