Sleep disordered breathing: OSA, CSA, Pathophysiology and Diagnosis.

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dc.contributor.authorVijayan, V K
dc.date.accessioned2016-10-18T08:47:22Z
dc.date.available2016-10-18T08:47:22Z
dc.date.issued2013-07
dc.description.abstractObstructive sleep apnea syndrome (OSAS) is a prevalent disorder that has been reported to occur in 2 to 4% of middle-aged adults. A similar prevalence of OSAS has been reported from India as well. However, this condition is frequently unrecognized and underdiagnosed. Important pathophysiological changes in patients with obstructive sleep apnea (OSA) is an alteration in human upper airway leading to a reduction in cross-sectional area of the upper airway contributing to the easy collapsibility of upper airway during sleep. Other pathophysiological changes in OSA are oxidative stress, systemic inflammation, sympathetic nerve activation, endothelial dysfunction, procoagulant activity, intrathoracic pressure changes and metabolic dysregulation. The gold standard for diagnosis of OSA is full polysomnography.en_US
dc.identifier.citationVijayan V K. Sleep disordered breathing: OSA, CSA, Pathophysiology and Diagnosis. Annals of the National Academy of Medical Sciences (India). 2013 Jul-Dec; 49(3&4): 92-102.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/177868
dc.language.isoenen_US
dc.source.urihttps://annals-nams.in/index.php/annals/article/view/5en_US
dc.subjectObstructive sleep apneaen_US
dc.subjectCentral sleep apneaen_US
dc.subjectOxidative stressen_US
dc.subjectMetabolic dysregulationen_US
dc.subjectPolysomnographyen_US
dc.titleSleep disordered breathing: OSA, CSA, Pathophysiology and Diagnosis.en_US
dc.typeArticleen_US
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