Mono and dual therapy for Helicobacter pylori associated gastritis.

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dc.contributor.authorGill, H Hen_US
dc.contributor.authorDesai, H Gen_US
dc.contributor.authorMehta, P Ren_US
dc.contributor.authorRanganathan, Sen_US
dc.contributor.authorKalro, R Hen_US
dc.contributor.authorMurti, P Ken_US
dc.contributor.authorPrabhu, S Ren_US
dc.date.accessioned1991-10-01en_US
dc.date.accessioned2009-05-31T00:40:28Z
dc.date.available1991-10-01en_US
dc.date.available2009-05-31T00:40:28Z
dc.date.issued1991-10-01en_US
dc.description.abstractSixty patients with Helicobacter Pylori positive non ulcer dyspepsia were randomly allocated to one of the following treatment groups: Group I--norfloxacin 400 mg bid for 10 days, Group II--amoxycillin 500 mg bid plus tinidazole 500 mg bid for 15 days, Group III--colloidal bismuth subcitrate (CBS) 240 mg bid for 4 weeks. H pylori elimination was achieved in 14%, 81%, and 62% in Groups I, II and III respectively. Eradication of H pylori was not observed in Groups I and II, but was achieved in 25% of patients in Group III. Antral gastritis improved in 69% in Group II and 50% in Group III. We conclude that norfloxacin is not effective in H pylori infection. A combination of amoxycillin and tinidazole is highly effective in H pylori elimination with improvement in associated gastritis, but H pylori eradication is not observed with this therapy. CBS is also effective in H pylori elimination though H pylori eradication is achieved in only 25%.en_US
dc.description.affiliationDepartment of Gastroenterology, BYL Nair Hospital, Bombay.en_US
dc.identifier.citationGill HH, Desai HG, Mehta PR, Ranganathan S, Kalro RH, Murti PK, Prabhu SR. Mono and dual therapy for Helicobacter pylori associated gastritis. Journal of the Association of Physicians of India. 1991 Oct; 39(10): 743-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/91511
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAmoxicillin --therapeutic useen_US
dc.subject.meshAntacids --therapeutic useen_US
dc.subject.meshAnti-Bacterial Agents --therapeutic useen_US
dc.subject.meshAnti-Ulcer Agents --therapeutic useen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshGastritis --drug therapyen_US
dc.subject.meshHelicobacter Infections --drug therapyen_US
dc.subject.meshHelicobacter pylori --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshNorfloxacin --therapeutic useen_US
dc.subject.meshOrganometallic Compounds --therapeutic useen_US
dc.subject.meshTinidazole --therapeutic useen_US
dc.titleMono and dual therapy for Helicobacter pylori associated gastritis.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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