Study of Prevalence of Pulmonary Artery Hypertension in Portal Hypertensives Patients in RIMS, Ranchi

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dc.contributor.authorKumar, Prakashen_US
dc.contributor.authorMayaen_US
dc.date.accessioned2020-09-24T07:24:54Z
dc.date.available2020-09-24T07:24:54Z
dc.date.issued2019-03
dc.description.abstractBackground: The development of pulmonary hypertension i.e.mean pulmonary artery pressure (mPAP) above 25 mmHg withnormal capillary wedge pressure and pulmonary vascularresistance(PVR) above 240 dyn/s/cm−5 in association withelevated pressure in portal circulation is known asportopulmonary hypertension (POPH). Comparing withidiopathic PAH, patients with POPH have a worst survivalprofile, with a 3-year survival of only 38% versus78% foridiopathic PAH. Recent evidence from France shows thatPOPH is the fourth most common form of PAH reported overallin the population-based French National Registry, afteridiopathic PAH and PAH associated with connective tissuediseases and con- genital heart disease. The aim of this studyis to evaluate frequency of POPH in portal hypertensivepatient.Materials and Methods: A cross sectional study of patientadmitted in RIMS, medicine department was performedfulfilling features of portal hypertension with ultrasoundshowing splenomegaly, ascites, portal vein diameter more than13 mm, portal vein velocity less than 15 cm/s and uppergastrointestinal endoscopy showing esophageal varices andpatient with connective tissue disease, congenital heartdisease, left ventricular systolic or diastolic dysfunction,valvular heart disease, lungs disease, sleep related breathingdisorder, chronic hemolytic and myeloproliferative disorderwere excluded. All patient underwent screening withechocardiography for measuring pulmonary artery systolicpressure (PASP) and PASP more than 35 mmHg wereconsidered for POPH which was confirmed with right heartcatheterisation by measuring mean pulmonary artery pressure(mPAP) of more than 25 mmHg.Observation: Among forty-two patient in this study, there werethirty-three male patients and nine female patients. POPH wasseen three female and two male patients with total of five out offorty- two with prevalence of 11.9% out of which 7.1% werefemale and 4.8% were male.Conclusion: Portopulmonary hypertension prevalence is 2–6%. In this study pulmonary hypertension is significantly high inportal hypertensive patient with percentage of 11.9% and moreprevalent in female.en_US
dc.identifier.affiliationsMD Medicine, DM Cardiology, Associate Professor, Department of Cardiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, Indiaen_US
dc.identifier.affiliationsMD Medicine, Senior Resident, Department of Cardiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, Indiaen_US
dc.identifier.citationKumar Prakash, Maya. Study of Prevalence of Pulmonary Artery Hypertension in Portal Hypertensives Patients in RIMS, Ranchi. International Journal of Medical Research Professionals. 2019 Mar; 5(2): 272-275en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203168
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org//10.21276/ijmrp.2019.5.2.062en_US
dc.subjectPortopulmonary Hypertension (POPH)en_US
dc.subjectPulmonary Arterial Hypertension (PAH)en_US
dc.subjectPulmonary Artery Systolic Pressure (PASP)en_US
dc.subjectMean Pulmonary Artery Pressure (mPAP)en_US
dc.subjectPulmonary Vascular Resistance (PVR).en_US
dc.titleStudy of Prevalence of Pulmonary Artery Hypertension in Portal Hypertensives Patients in RIMS, Ranchien_US
dc.typeJournal Articleen_US
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