Management of benzodiazepine dependence and toxicity.

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dc.contributor.authorShohel, Mohammad
dc.contributor.authorShoaib-Ul-Islam
dc.contributor.authorWadud, Rasiqh
dc.contributor.authorHabib, Zaki Farhad
dc.contributor.authorMalik, Farjana
dc.contributor.authorKabir, Sanjana
dc.contributor.authorReza, Hasan Mahmud
dc.date.accessioned2014-06-03T12:37:24Z
dc.date.available2014-06-03T12:37:24Z
dc.date.issued2013-06
dc.description.abstractThe key target of this review is to compare the efficacies of the different adjuncts and methods used in the management of benzodiazepine dependence (tolerance and withdrawal) and poisoning. A systemic review of randomized controlled trials was carried out to determine which method of adjuvant therapy can be best used to overcome the withdrawal symptoms exhibited during benzodiazepine discontinuation. In addition, different tapering methods employed have also been presented in this review. Zolpidem in combination with cognitive behavioural therapy with a parallel gradual taper after conversion to long half-life Benzodiazepine seems to be a promising method among the several analysed. Finally the efficacies of the two available methods to combat benzodiazepine toxicity, namely flumazenil and naloxone have been discussed and compared.en_US
dc.identifier.citationShohel Mohammad, Shoaib-Ul-Islam, Wadud Rasiqh, Habib Zaki Farhad, Malik Farjana, Kabir Sanjana, Reza Hasan Mahmud. Management of benzodiazepine dependence and toxicity. Journal of Applied Pharmaceutical Science. 2013 June; 3(6): 146-151.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/151668
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=939en_US
dc.subjectBenzodiazepineen_US
dc.subjecttoxicityen_US
dc.subjecttaperingen_US
dc.subjectwithdrawal symptomsen_US
dc.subjectdependenceen_US
dc.subjecttoleranceen_US
dc.titleManagement of benzodiazepine dependence and toxicity.en_US
dc.typeArticleen_US
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