Acute renal failure in severe exertional rhabdomyolysis.

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dc.contributor.authorUberoi, H Sen_US
dc.contributor.authorDugal, J Sen_US
dc.contributor.authorKasthuri, A Sen_US
dc.contributor.authorKolhe, V Sen_US
dc.contributor.authorKumar, A Ken_US
dc.contributor.authorCruz, S Aen_US
dc.date.accessioned1991-09-01en_US
dc.date.accessioned2009-05-30T23:29:10Z
dc.date.available1991-09-01en_US
dc.date.available2009-05-30T23:29:10Z
dc.date.issued1991-09-01en_US
dc.description.abstractDuring the last 6 years, 7 healthy individuals who were reasonably well acclimatised to physical exertion came under observation with acute renal failure due to exercise induced myoglobinuria. Their mean age was 20 years, and renal failure resulted after cross country run of 10-15 km in 6 cases and long route march of 90 km in 3 days in one case. There was no evidence of effects of heat, dehydration or hypotension. Apart from myoglobinuria and significant urinary sediments, serum aldolase (mean 69.0 SL u/ml) and serum creatinine phosphokinase (mean 120.0 Sigma u/ml) were also elevated. Maximum blood urea and creatinine were 224 mg/dl and 13.9 mg/dl respectively. Hypocalcaemia was noticed in 3 cases, hyperkalaemia in 4 cases and hyperuricaemia in one case during the oliguric phase. One case had features of non-oliguric acute renal failure. All cases recovered though 4 cases required dialysis support. Kidney biopsy in 3 cases showed recovering acute tubular necrosis with eosinophilic material in tubules. Lactate studies in the convalescent period revealed normal response and repeat physical exertion of same severity after 6 months did not reproduce the syndrome. It is concluded that exertional rhabdomyolysis unassociated with heat stress is a rare entity, and with prompt diagnosis and energic management results are rewarding.en_US
dc.description.affiliationDepartment of Medicine, Command Hospital, Pune.en_US
dc.identifier.citationUberoi HS, Dugal JS, Kasthuri AS, Kolhe VS, Kumar AK, Cruz SA. Acute renal failure in severe exertional rhabdomyolysis. Journal of the Association of Physicians of India. 1991 Sep; 39(9): 677-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/90467
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Failure, Acute --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMyoglobinuria --etiologyen_US
dc.subject.meshPhysical Exertionen_US
dc.subject.meshRhabdomyolysis --epidemiologyen_US
dc.subject.meshRunningen_US
dc.subject.meshStress, Physiological --complicationsen_US
dc.titleAcute renal failure in severe exertional rhabdomyolysis.en_US
dc.typeJournal Articleen_US
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