Seroprevalence of cytomegalovirus infection in children born to HIV-1 infected women.

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dc.contributor.authorLikitnukul, Sasithornen_US
dc.contributor.authorBhattarakosol, Parvapanen_US
dc.contributor.authorPoovorawan, Yongen_US
dc.date.accessioned2009-05-27T17:19:52Z
dc.date.available2009-05-27T17:19:52Z
dc.date.issued2003-06-25en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractCytomegalovirus (CMV) is a frequent opportunistic infectious agent in children infected with human immunodeficiency virus type 1 (HIV-1). It has been implicated as a factor in the progression of HIV-1 disease. The aim of the present study was to evaluate the prevalence of CMV infection in Thai children born to HIV-1 infected women. The prevalence of CMV infection was 13, 89 and 84% in HIV-infected children and 9, 61 and 75% in HIV uninfected at age ranges of 0-12, 13-36 and 37-79 months, respectively. The prevalence of CMV infection was significantly different between HIV infected children (89%) and HIV uninfected (61%) at the age of 13-36 months (p < 0.05). The presence of CMV IgM in some children of age < 1 year suggested that CMV infection could occur early in life. Early co-infection may be important as they remain a risk factor for reactivation of latent CMV infection throughout the course of the HIV diseases. Clinical monitoring and appropriate work up may be of benefit in the early diagnosis and treatment of CMV disease.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.en_US
dc.identifier.citationLikitnukul S, Bhattarakosol P, Poovorawan Y. Seroprevalence of cytomegalovirus infection in children born to HIV-1 infected women. Asian Pacific Journal of Allergy and Immunology. 2003 Jun; 21(2): 127-30en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36957
dc.language.isoengen_US
dc.subject.meshAIDS-Related Opportunistic Infections --immunologyen_US
dc.subject.meshAntibodies, Anti-Idiotypic --immunologyen_US
dc.subject.meshAntibodies, Monoclonal --immunologyen_US
dc.subject.meshChild Welfareen_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCytomegalovirus Infections --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHIV Infections --immunologyen_US
dc.subject.meshHIV-1 --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant Welfareen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfectious Disease Transmission, Verticalen_US
dc.subject.meshMaleen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleSeroprevalence of cytomegalovirus infection in children born to HIV-1 infected women.en_US
dc.typeComparative Studyen_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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