Comparison of MRI Findings in Diabetic and Nondiabetic Patients with Rhino-Orbito-Cerebral Mucormycosis

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dc.contributor.authorAgrawal, Alkaen_US
dc.contributor.authorKori, Neetuen_US
dc.contributor.authorMadhpuriya, Gulshanen_US
dc.contributor.authorNigam, Prakharen_US
dc.contributor.authorAgrawal, Simranen_US
dc.date.accessioned2023-07-21T11:27:56Z
dc.date.available2023-07-21T11:27:56Z
dc.date.issued2022-10
dc.description.abstractObjective?Rhino-orbito-cerebral mucormycosis (ROCM) has emerged as a key concern during the period of coronavirus disease 2019 (COVID-19) pandemic. Diabetes mellitus is a known risk factor for invasive fungal infection. The aim of this article was to study and compare the radiological features of COVID-19-associated ROCM between diabetic and nondiabetic patients using magnetic resonance imaging. Materials and Methods?A retrospective observational study comprising 78 diabetics and 40 nondiabetics who developed ROCM after COVID-19 was conducted. The imaging data of both groups were analyzed, findings tabulated and compared using statistical methods. Results?Maxillary and ethmoid sinuses were commonly involved in both groups. Periantral fat and orbits were the most common sites of disease extension. The spread of infection to periantral soft tissue was significantly higher in diabetics (p = 0.049). Diabetics were more likely to have bone, orbit, and brain involvement than nondiabetics, although the difference was not statistically significant. Diabetic patients were the only ones to experience complications such as fungal abscess and cavernous sinus and internal carotid artery involvement. However, a considerable number of nondiabetic patients (22.5%) also had an intracranial extension of disease. Conclusion?The radiological appearances and common sites of invasion in ROCM are similar in diabetic and nondiabetic patients. The extensive spread of infection to extra-sinus regions can occur in nondiabetic patients with COVID-19 but is less frequent compared with diabetics.en_US
dc.identifier.affiliationsDepartment of Radiodiagnosis, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiodiagnosis, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiodiagnosis, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDr. D. Y. Patil Medical College, Kolhapur, Maharashtra, Indiaen_US
dc.identifier.citationAgrawal, Alkaen_US
dc.identifier.citationKori, Neetuen_US
dc.identifier.citationMadhpuriya, Gulshanen_US
dc.identifier.citationNigam, Prakharen_US
dc.identifier.citationAgrawal, Simran. Comparison of MRI Findings in Diabetic and Nondiabetic Patients with Rhino-Orbito-Cerebral Mucormycosis. Annals of the National Academy of Medical Sciences. 2022 Oct; 58(4): 204-209en_US
dc.identifier.issn0379-038X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220197
dc.languageenen_US
dc.publisherThieme Medical and Scientific Publishers Pvt. Ltden_US
dc.relation.issuenumber4en_US
dc.relation.volume58en_US
dc.source.urihttps://doi.org/10.1055/s-0042-1757740en_US
dc.subjectCOVID-19en_US
dc.subjectdiabetes mellitusen_US
dc.subjectmagnetic resonance imagingen_US
dc.subjectmucormycosisen_US
dc.titleComparison of MRI Findings in Diabetic and Nondiabetic Patients with Rhino-Orbito-Cerebral Mucormycosisen_US
dc.typeJournal Articleen_US
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