A clinico-pathological study of multidrug regimen in paucibacillary leprosy.

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dc.contributor.authorKar, P Ken_US
dc.contributor.authorJha, P Ken_US
dc.contributor.authorPanayach, J Sen_US
dc.contributor.authorSnehi, P Sen_US
dc.date.accessioned1988-04-01en_US
dc.date.accessioned2009-05-28T10:24:31Z
dc.date.available1988-04-01en_US
dc.date.available2009-05-28T10:24:31Z
dc.date.issued1988-04-01en_US
dc.description.abstractPreliminary results of a clinical trial in one hundred untreated paucibacillary leprosy cases with multidrug therapy (MDT) as per WHO recommendation are presented. Out of 100 fresh cases studied 18 had indeterminate, 35 tuberculoid and 47 cases had borderline tuberculoid leprosy. All were given MDT consisting of rifampicin 600 mg once a month and dapsone 100 mg daily for six months. At the end of six months all the cases were evaluated clinically and histopathological examination of lesions were studied. The lesions were still active in 35% of patient clinically and 47% histologically. Complete histological resolution have come across only in 4 cases suffering from indeterminate leprosy. Altogether 65% cases receiving MDT have shown marked improvement to total inactivation. Histologically, lymphocytic infiltration still persisted in 90% of slides examined and nerve infiltration were still present in 64% of cases at the end of six months receiving MDT.en_US
dc.description.affiliationDepartment of Dermatology, STD and Leprosy, Base Hospital, Lucknow.en_US
dc.identifier.citationKar PK, Jha PK, Panayach JS, Snehi PS. A clinico-pathological study of multidrug regimen in paucibacillary leprosy. Indian Journal of Leprosy. 1988 Apr; 60(2): 235-41en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/55287
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshDapsone --administration & dosageen_US
dc.subject.meshDrug Administration Scheduleen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeprosy --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRemission Inductionen_US
dc.subject.meshRifampin --administration & dosageen_US
dc.titleA clinico-pathological study of multidrug regimen in paucibacillary leprosy.en_US
dc.typeJournal Articleen_US
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