A study of the haematologic spectrum of myelodysplastic syndrome.

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dc.contributor.authorKini, Jen_US
dc.contributor.authorKhadilkar, U Nen_US
dc.contributor.authorDayal, J Pen_US
dc.date.accessioned2001-01-04en_US
dc.date.accessioned2009-05-29T13:24:09Z
dc.date.available2001-01-04en_US
dc.date.available2009-05-29T13:24:09Z
dc.date.issued2001-01-04en_US
dc.description.abstractIn 31 patients of myelodysplastic syndrome, RAEB-t was the commonest subtype (29%), and RARS, the lease common (6.4%); 19.4% were characterised as the unclassifiable (UC) group. Pallor was the dominant sign (90.3%). Low haemoglobin in RA & RARS (p<0.05), thrombocytopenia in RAEB-t (p<0.01) and high leuco/monocyte counts in CMML (p<0.001) were observed. Neutropenia occurred most frequently in RAEB & RAEB-t and circulating blasts in all cases of RAEB-t and CMML. Bicytopenia was the commonest finding (58.1%) and pancytopenia the least (16.1%). 84% of marrows were hypercellular and trilineage dysplasia was seen in 68% of patients. Megaloblastoid dyserythropoiesis was the predominant feature in all cases, dysgranulopoiesis in all cases of RAEB, RAEB-t and CMML, and micromegokaryocytes in all cases of RARS, RAEB & CMML were seen. RAEB-t and RAEB (33.3% each) were the predominant groups which progressed to leukemia, FAB AML-M2, being the commonest type (60%).en_US
dc.description.affiliationDepartment of Pathology, Kottayam Medical College, Kottayam.en_US
dc.identifier.citationKini J, Khadilkar UN, Dayal JP. A study of the haematologic spectrum of myelodysplastic syndrome. Indian Journal of Pathology & Microbiology. 2001 Jan; 44(1): 9-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/75610
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshBone Marrow --pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHematologic Testsen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia --etiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMyelodysplastic Syndromes --blooden_US
dc.subject.meshNeutropenia --etiologyen_US
dc.subject.meshPancytopenia --etiologyen_US
dc.subject.meshPrognosisen_US
dc.subject.meshThrombocytopenia --etiologyen_US
dc.titleA study of the haematologic spectrum of myelodysplastic syndrome.en_US
dc.typeJournal Articleen_US
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