Plasmid mediated multidrug resistance in Salmonella typhi.

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dc.contributor.authorJesudason, M Ven_US
dc.contributor.authorJohn, T Jen_US
dc.date.accessioned1992-03-01en_US
dc.date.accessioned2009-05-27T07:03:05Z
dc.date.available1992-03-01en_US
dc.date.available2009-05-27T07:03:05Z
dc.date.issued1992-03-01en_US
dc.description.abstractBetween September 1989 and February 1991, strains of S. typhi showing multiple drug resistance were isolated from blood cultures of patients with typhoid fever. A total of 283 isolates were obtained over a period of 18 months. Forty four (11%) of these isolates were resistant to chloramphenicol, ampicillin, co-trimoxazole and tetracycline, the first three being drugs currently used in treating typhoid fever. Forty of the 44 multi-resistant strains tested showed transfer of resistance 'en block' to recipient Escherichia coli K 12 (J62-2). All 44 multi-resistant strains were sensitive to ciprofloxacin and ofloxacin. Since the resistance is plasmid-mediated, the problem is likely to get aggravated.en_US
dc.description.affiliationDepartment of Microbiology, Christian Medical College Hospital, Vellore.en_US
dc.identifier.citationJesudason MV, John TJ. Plasmid mediated multidrug resistance in Salmonella typhi. Indian Journal of Medical Research. 1992 Mar; 95(): 66-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19087
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAmpicillin Resistance --geneticsen_US
dc.subject.meshChloramphenicol Resistance --geneticsen_US
dc.subject.meshDrug Resistance, Microbial --geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshR Factorsen_US
dc.subject.meshSalmonella typhi --drug effectsen_US
dc.subject.meshTetracycline Resistance --geneticsen_US
dc.subject.meshTrimethoprim-Sulfamethoxazole Combination --pharmacologyen_US
dc.subject.meshTyphoid Fever --microbiologyen_US
dc.titlePlasmid mediated multidrug resistance in Salmonella typhi.en_US
dc.typeJournal Articleen_US
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