Hepatitis B induced fulminant liver failure: A call for prevention

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dc.contributor.authorSingh, Bhupinderen_US
dc.contributor.authorSingh, Jugrajen_US
dc.contributor.authorBansal, Kabiren_US
dc.contributor.authorVerma, Sakshien_US
dc.contributor.authorBali, Kusumen_US
dc.contributor.authorKaur, Navjoten_US
dc.date.accessioned2023-08-09T06:16:11Z
dc.date.available2023-08-09T06:16:11Z
dc.date.issued2023-07
dc.description.abstractAcute fulminant hepatic failure is a condition in which a healthy liver deteriorates rapidly following an insult, resulting in the impairment of its synthetic functions. This condition is rare and is associated with high fatality rates. We report the case of a 19-year-old male who was brought to the emergency room in an unconscious state with jaundice and persistent fever for 2–3 weeks after recently commencing intravenous use of morphine. He was found to be hepatitis B surface antigen reactive, and his laboratory tests indicated severe liver dysfunction with elevated levels of serum bilirubin, aspartate transaminase, alanine transaminase, gamma-glutamyl transferase, and International normalized ratio. The patient was diagnosed with fulminant liver failure with coagulopathy and hepatic encephalopathy. The patient’s family was addressed and counseled regarding the urgent need for liver transplantation. However, due to a lack of funds and insurance, supportive treatment was the only option left. Despite all supportive measures, the patient expired within 48 h. This case highlights the importance of various socioeconomic issues involved with liver transplantation, as in a resource-limited setting, urgent transplantation seems nearly impossible. In addition, this case report raises certain ethical issues that need consideration, particularly in an injection drug use scenario. It also highlights the importance of addressing the rising issue of injection drug use among youth, particularly in the regions of Punjab.en_US
dc.identifier.affiliationsJunior Residenten_US
dc.identifier.affiliationsInternen_US
dc.identifier.affiliationsProfessor, Department of Medicine, Punjab Institute of Medical Sciences, Jalandharen_US
dc.identifier.affiliationsMedical Officer, Department of Medicine, Aastha Hospital, Jalandharen_US
dc.identifier.affiliationsGraduate, Department of Medicine, Government Medical College, Amritsaren_US
dc.identifier.affiliationsMedical Officer, Department of Medicine, S. Ram Singh Memorial Babbar Multispeciality Hospital, Guurdaspur, Punjab, Indiaen_US
dc.identifier.citationSingh Bhupinder, Singh Jugraj, Bansal Kabir, Verma Sakshi, Bali Kusum, Kaur Navjot. Hepatitis B induced fulminant liver failure: A call for prevention. Indian Journal of Case Reports. 2023 July; 9(7): 217-219en_US
dc.identifier.issn2454-1303
dc.identifier.issn2454-129X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222341
dc.languageenen_US
dc.publisherMansa STM Publishersen_US
dc.relation.issuenumber7en_US
dc.relation.volume9en_US
dc.source.urihttps://mansapublishers.com/index.php/ijcr/article/view/4093en_US
dc.subjectFulminant liver failureen_US
dc.subjectHepatitis Ben_US
dc.subjectInjection drug useen_US
dc.subjectLiver transplantationen_US
dc.titleHepatitis B induced fulminant liver failure: A call for preventionen_US
dc.typeJournal Articleen_US
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