Outcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitis

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dc.contributor.authorAhsan, S M Mortazaen_US
dc.contributor.authorDas, Bidhan C.en_US
dc.contributor.authorNur, Asaduzzamanen_US
dc.contributor.authorZannat, Noor Een_US
dc.contributor.authorMahmud, Raselen_US
dc.contributor.authorSiddique, Nur Alamen_US
dc.contributor.authorSobhan, Sarwar Ahmeden_US
dc.contributor.authorKhan, Emrul Hasanen_US
dc.contributor.authorSiddique, Omaren_US
dc.date.accessioned2023-07-21T11:25:42Z
dc.date.available2023-07-21T11:25:42Z
dc.date.issued2022-06
dc.description.abstractBackground: Outcome of drainage operation for chronic pancreatitis are variable. The present study is taken to observe effect of longitudinal pancreatico-jejunostomy (LPJ) on pain control and pancreatic function in chronic pancreatitis in our setting.Material & Methods:Thirty-three patients who underwent LPJ for symptomatic chronic pancreatitis for one year period presented with abdominal pain (100%), steatorrhoea (30.3%), diabetes (66.7%) and weight loss (78.8%). Definitive diagnosis was made on the basis of ultrasonography and MRCP findings. LPJ (Partingtong-Rochelle) operation was done in all patients. Pain (using visual analoge scale), glycemic status (using FBS, 2hABF, HbA1c), body weight, serum zinc levels (as a marker of exocrine function), and serum insulin level (as a marker of endocrine function) were measured immediately after admission and 3 months after operation.Results:Three months after operation pain was completely disappeared in 23 (69.7%) patients, it persisted in different grade in 10 (30.3%) patients and the pain reduction rate was significant. Twenty two patients who had diabetes prior to surgery, their glycemic status significantly decreased and serum insulin level significantly increased (preoperative; 7.1�1 礥/L, postoperative; 14.3�礥/L) in 22 patients with DM after surgery. Serum zinc level increased (preoperative; 80.8�.5 礸/dl, postoperative; 85.3�.7 礸/dl) 3 months after surgery but the difference was not significant (p=0.571). However the body weight of all patients were significantly increased after operation.Conclusions:LPJ reduces abdominal pain and improves both exocrine and endocrine function in patient with chronic pancreatitis. Serum zinc levels can be considered as a tool of exocrine function.en_US
dc.identifier.affiliationsMedical Officer, Sheikh Russel National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh. Email: mortazaahsan@gmail.com, Orcid ID: 0000-0002-2034-9328en_US
dc.identifier.affiliationsProfessor, Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: dbidhan@yahoo.com, Orcid ID: 0000-0003-0956-9095en_US
dc.identifier.affiliationsAssistant professor, Department of Hepatobiliary Surgery, Enam medical college Hospital, Savar, Dhaka, Bangladesh. Email: Nahid2532@gmail.com, Orcid ID: 0000-0002-4064-4885en_US
dc.identifier.affiliationsPhase B Resident, Department of Paediatric Nephrology, Bangladesh Institute of Child Health, Shyamoli, Dhaka, Bangladesh. Email: drnoorezannat@gmail.com, Orcid ID: 0000-0002-3920-6861en_US
dc.identifier.affiliationsMedical officer, Sylhet M. A. G. Osmani Medical College, Sylhet, Bangladesh. Email: Raselmmc36@gmail.com, Orcid ID: 0000-0003-4979-6823en_US
dc.identifier.affiliationsPhase B student (HBP-surgery), Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: nuralamarif@gmail.com, Orcid ID: 0000-0001-7098-8462en_US
dc.identifier.affiliationsMedical Officer, (HBP-surgery), Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: rubai.dmc59@gmail.com, Orcid ID: 0000-0001-9040-0136en_US
dc.identifier.affiliationsAssociate professor, Department of Hepatobiliary and Pancreatic Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh. Email: dremrul@gamil.com Orcid ID: 0000-0003-1802-6260.en_US
dc.identifier.affiliationsJunior Consultant, Department of Surgery, Keraniganj Upazilla Health Complex, Dhaka, Bangladesh. Email: Omar24th@gmail.com, Orcid ID: 0000-0002-2976-3488.en_US
dc.identifier.citationAhsan S M Mortaza, Das Bidhan C., Nur Asaduzzaman, Zannat Noor E, Mahmud Rasel, Siddique Nur Alam, Sobhan Sarwar Ahmed, Khan Emrul Hasan, Siddique Omar. Outcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitis. Annals of International Medical and Dental Research. 2022 Jun; 8(3): 48-54en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219975
dc.languageenen_US
dc.publisherScholars Publisheren_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.53339/aimdr.2022.8.3.7en_US
dc.subjectChronic pancreatitisen_US
dc.subjectLPJen_US
dc.subjectPain controlen_US
dc.subjectpancreatic function.en_US
dc.titleOutcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitisen_US
dc.typeJournal Articleen_US
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