Outcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitis
dc.contributor.author | Ahsan, S M Mortaza | en_US |
dc.contributor.author | Das, Bidhan C. | en_US |
dc.contributor.author | Nur, Asaduzzaman | en_US |
dc.contributor.author | Zannat, Noor E | en_US |
dc.contributor.author | Mahmud, Rasel | en_US |
dc.contributor.author | Siddique, Nur Alam | en_US |
dc.contributor.author | Sobhan, Sarwar Ahmed | en_US |
dc.contributor.author | Khan, Emrul Hasan | en_US |
dc.contributor.author | Siddique, Omar | en_US |
dc.date.accessioned | 2023-07-21T11:25:42Z | |
dc.date.available | 2023-07-21T11:25:42Z | |
dc.date.issued | 2022-06 | |
dc.description.abstract | Background: Outcome of drainage operation for chronic pancreatitis are variable. The present study is taken to observe effect of longitudinal pancreatico-jejunostomy (LPJ) on pain control and pancreatic function in chronic pancreatitis in our setting.Material & Methods:Thirty-three patients who underwent LPJ for symptomatic chronic pancreatitis for one year period presented with abdominal pain (100%), steatorrhoea (30.3%), diabetes (66.7%) and weight loss (78.8%). Definitive diagnosis was made on the basis of ultrasonography and MRCP findings. LPJ (Partingtong-Rochelle) operation was done in all patients. Pain (using visual analoge scale), glycemic status (using FBS, 2hABF, HbA1c), body weight, serum zinc levels (as a marker of exocrine function), and serum insulin level (as a marker of endocrine function) were measured immediately after admission and 3 months after operation.Results:Three months after operation pain was completely disappeared in 23 (69.7%) patients, it persisted in different grade in 10 (30.3%) patients and the pain reduction rate was significant. Twenty two patients who had diabetes prior to surgery, their glycemic status significantly decreased and serum insulin level significantly increased (preoperative; 7.1�1 礥/L, postoperative; 14.3�礥/L) in 22 patients with DM after surgery. Serum zinc level increased (preoperative; 80.8�.5 礸/dl, postoperative; 85.3�.7 礸/dl) 3 months after surgery but the difference was not significant (p=0.571). However the body weight of all patients were significantly increased after operation.Conclusions:LPJ reduces abdominal pain and improves both exocrine and endocrine function in patient with chronic pancreatitis. Serum zinc levels can be considered as a tool of exocrine function. | en_US |
dc.identifier.affiliations | Medical Officer, Sheikh Russel National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh. Email: mortazaahsan@gmail.com, Orcid ID: 0000-0002-2034-9328 | en_US |
dc.identifier.affiliations | Professor, Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: dbidhan@yahoo.com, Orcid ID: 0000-0003-0956-9095 | en_US |
dc.identifier.affiliations | Assistant professor, Department of Hepatobiliary Surgery, Enam medical college Hospital, Savar, Dhaka, Bangladesh. Email: Nahid2532@gmail.com, Orcid ID: 0000-0002-4064-4885 | en_US |
dc.identifier.affiliations | Phase B Resident, Department of Paediatric Nephrology, Bangladesh Institute of Child Health, Shyamoli, Dhaka, Bangladesh. Email: drnoorezannat@gmail.com, Orcid ID: 0000-0002-3920-6861 | en_US |
dc.identifier.affiliations | Medical officer, Sylhet M. A. G. Osmani Medical College, Sylhet, Bangladesh. Email: Raselmmc36@gmail.com, Orcid ID: 0000-0003-4979-6823 | en_US |
dc.identifier.affiliations | Phase B student (HBP-surgery), Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: nuralamarif@gmail.com, Orcid ID: 0000-0001-7098-8462 | en_US |
dc.identifier.affiliations | Medical Officer, (HBP-surgery), Department of Hepatobiliary-Pancreatic and Liver Transplant Surgery, BSMMU, Dhaka, Bangladesh. Email: rubai.dmc59@gmail.com, Orcid ID: 0000-0001-9040-0136 | en_US |
dc.identifier.affiliations | Associate professor, Department of Hepatobiliary and Pancreatic Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh. Email: dremrul@gamil.com Orcid ID: 0000-0003-1802-6260. | en_US |
dc.identifier.affiliations | Junior Consultant, Department of Surgery, Keraniganj Upazilla Health Complex, Dhaka, Bangladesh. Email: Omar24th@gmail.com, Orcid ID: 0000-0002-2976-3488. | en_US |
dc.identifier.citation | Ahsan S M Mortaza, Das Bidhan C., Nur Asaduzzaman, Zannat Noor E, Mahmud Rasel, Siddique Nur Alam, Sobhan Sarwar Ahmed, Khan Emrul Hasan, Siddique Omar. Outcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitis. Annals of International Medical and Dental Research. 2022 Jun; 8(3): 48-54 | en_US |
dc.identifier.issn | 2395-2822 | |
dc.identifier.issn | 2395-2814 | |
dc.identifier.place | India | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/219975 | |
dc.language | en | en_US |
dc.publisher | Scholars Publisher | en_US |
dc.relation.issuenumber | 3 | en_US |
dc.relation.volume | 8 | en_US |
dc.source.uri | https://doi.org/10.53339/aimdr.2022.8.3.7 | en_US |
dc.subject | Chronic pancreatitis | en_US |
dc.subject | LPJ | en_US |
dc.subject | Pain control | en_US |
dc.subject | pancreatic function. | en_US |
dc.title | Outcome of Longitudinal Pancreatico-Jejunostomy on Pain Control and Pancreatic Function in Chronic Pancreatitis | en_US |
dc.type | Journal Article | en_US |
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