Study on Comparative Effects of Rocuronium and Succinylcholine During Rapid Sequence Intubation

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dc.contributor.authorPatil, Bhaidas Onkaren_US
dc.contributor.authorSonavdekar, Suhasini Ravindraen_US
dc.contributor.authorMathur, Ranjanen_US
dc.contributor.authorAcharya, Jitendraen_US
dc.date.accessioned2020-09-24T07:25:35Z
dc.date.available2020-09-24T07:25:35Z
dc.date.issued2019-07
dc.description.abstractBackground: Patients frequently need a rapid sequenceinduction (RSI) endotracheal intubation technique duringemergencies or electively to protect against aspiration inconditions like pregnancy, abdominal pathologies especiallyobstruction or ileus, neurologic disease, or in difficult airway.Traditionally succinylcholine has been the most commonlyused muscle relaxant for this purpose because of its fast onsetand short duration; unfortunately, it can have serious sideeffects. Rocuronium has been suggested as an alternative tosuccinylcholine for intubation.Methods: This study was done at department of anesthesiaSMBT Institute of Medical Science and Research Center,Dhamangaon Tal. Igatpuri, Nashik, Maharashtra, India. Thepatients were systematically randomized into three groups oftwenty each. Group A: Succinylcholine 1.5 mg/kg, Group B:Rocuronium bromide 0.6 mg/kg &Group C: Rocuroniumbromide 0.9 mg/kg.Intubating conditions, onset of action andadverse effects were observed.Results: It was observed that group A & group C patients hadexcellent intubation conditions with faster onset of action forgroup A patients. Adverse effects were not seen in any of thethree groups.Conclusion: Our study concludes that Succinylcholine is anideal agent for intubation in all surgical procedures. Intubatingconditions of Rocuronium bromide at a dose of 0.9mg/kg(3xED95) is comparable to Succinylcholine 1.5mg/kgat1minute. Rocuronium bromide 0.9mg/kg can be used safelyin patients where succinylcholine is contraindicated.en_US
dc.identifier.affiliationsAssociate Professor, Department of Anaesthesia, SMBT Institute of Medical Sciences & Research Center, Igatpuri, Nashik, Maharashtra, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of Anaesthesia, MGM Medical College, Kamothe, Navi Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsSenior Professor and Head, 4Senior Demonstrator, Department of Dentistry, S. P. Medical College, Bikaner, Rajasthan, India.en_US
dc.identifier.citationPatil Bhaidas Onkar, Sonavdekar Suhasini Ravindra, Mathur Ranjan, Acharya Jitendra. Study on Comparative Effects of Rocuronium and Succinylcholine During Rapid Sequence Intubation. International Journal of Medical Research Professionals. 2019 Jul; 5(4): 24-27en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203388
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org//10.21276/ijmrp.2019.5.4.005en_US
dc.subjectSuccinylcholineen_US
dc.subjectIntubationen_US
dc.subjectRocuronium.en_US
dc.titleStudy on Comparative Effects of Rocuronium and Succinylcholine During Rapid Sequence Intubationen_US
dc.typeJournal Articleen_US
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