Pattern of relapses in sporozoite induced Plasmodium cynomolgi B infection in rhesus monkeys.

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dc.contributor.authorPuri, S Ken_US
dc.contributor.authorSharma, Pen_US
dc.contributor.authorDutta, G Pen_US
dc.date.accessioned1990-06-01en_US
dc.date.accessioned2009-06-01T18:13:10Z
dc.date.available1990-06-01en_US
dc.date.available2009-06-01T18:13:10Z
dc.date.issued1990-06-01en_US
dc.description.abstractThe pattern of sequential relapses in 10 rhesus monkeys following inoculation of sporozoites of Plasmodium cynomolgi B has been studied after administering curative dose of chloroquine (5 mg/kg base X 7 days) to eliminate blood parasitaemia after each relapse. Observation for periods ranging from 109 to 245 days showed that the interval between first six relapses was 19.3 +/- 6.77 days (1st relapse), 20.9 +/- 8.43 days (2nd relapse), 22.8 +/- 8.55 days (3rd relapse), 27.8 +/- 10.0 days (4th relapse), 31.67 +/- 11.50 days (5th relapse) and 32.5 +/- 16.26 days (6th relapse). The results of this study indicate a gradual extension of the relapse interval in successive relapses.en_US
dc.identifier.citationPuri SK, Sharma P, Dutta GP. Pattern of relapses in sporozoite induced Plasmodium cynomolgi B infection in rhesus monkeys. Journal of Communicable Diseases. 1990 Jun; 22(2): 98-101en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/112065
dc.language.isoengen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChloroquine --therapeutic useen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshMacaca mulattaen_US
dc.subject.meshMalaria --drug therapyen_US
dc.subject.meshRecurrenceen_US
dc.subject.meshTime Factorsen_US
dc.titlePattern of relapses in sporozoite induced Plasmodium cynomolgi B infection in rhesus monkeys.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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