Effect of bronchodilators on surfactant system of lung.

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dc.contributor.authorRao, G Jen_US
dc.contributor.authorAroor, A Ren_US
dc.contributor.authorRao, A Ken_US
dc.contributor.authorSolankar, Sen_US
dc.date.accessioned1989-08-01en_US
dc.date.accessioned2009-05-27T07:08:41Z
dc.date.available1989-08-01en_US
dc.date.available2009-05-27T07:08:41Z
dc.date.issued1989-08-01en_US
dc.description.abstractPulmonary surfactant activity of healthy male albino rats was estimated in terms of the maximum and minimum surface tension values of alveolar washings and the phospholipid content of the extract. The results obtained in these (control) animals were compared with those in three groups of animals treated with therapeutic doses of terbutaline, adrenaline and aminophylline. A significant decrease in the surface tension values without a significant increase in the phospholipid content was observed with aminophylline, whereas a significant increase in phospholipid concentration without a significant decrease in surface tension values was observed in case of terbutaline and adrenaline. These findings suggest that aminophylline, in addition to a bronchodilator action, lowers the elastic resistance of lung. The study also indicates caution in interpreting phospholipid concentration as surfactant activity.en_US
dc.identifier.citationRao GJ, Aroor AR, Rao AK, Solankar S. Effect of bronchodilators on surfactant system of lung. Indian Journal of Medical Research. 1989 Aug; 90(): 266-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19485
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAminophylline --pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBronchodilator Agents --pharmacologyen_US
dc.subject.meshEpinephrine --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPhospholipids --analysisen_US
dc.subject.meshPulmonary Surfactants --drug effectsen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.subject.meshTerbutaline --pharmacologyen_US
dc.titleEffect of bronchodilators on surfactant system of lung.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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